Results 1 to 10 of about 331,678 (120)

Setmelanotide – from genes to targeted therapy in some rare forms of obesity [PDF]

open access: yesFarmacja Polska, 2021
Obesity is a serious public health concern. It significantly affects an individual’s quality of life and is associated with an increased risk of developing other conditions, including diabetes, hypertension, and cardiovascular complications.
Dawid Frączkowski
doaj   +1 more source

Bakuchiol: następca retinolu

open access: yesHerbalism, 2023
Zmarszczki i przebarwienia to widoczne skutki fotostarzenia skóry, którego mechanizmy omówiono pokrótce w poniżej pracy. Dotychczas do zwalczania jego skutków używano aplikowany miejscowo retinol, znany w dermatologii związek, stosowany z powodzeniem w ...
Mateusz Grzelecki   +2 more
doaj   +1 more source

The Modus Operandi of Hydrogen Sulfide(H2S)-Dependent Protein Persulfidation in Higher Plants

open access: yesAntioxidants, 2021
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function.
Francisco J. Corpas   +4 more
doaj   +1 more source

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)

open access: yesFrontiers in Physiology, 2021
α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985.
Jesper Bergwik   +5 more
doaj   +1 more source

A Review of Manganese(III) (Oxyhydr)Oxides Use in Advanced Oxidation Processes

open access: yesMolecules, 2021
The key role of trivalent manganese (Mn(III)) species in promoting sulfate radical-based advanced oxidation processes (SR-AOPs) has recently attracted increasing attention.
Daqing Jia   +3 more
doaj   +1 more source

Antileishmanial Anthracene Endoperoxides: Efficacy In Vitro, Mechanisms and Structure-Activity Relationships

open access: yesMolecules, 2022
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells.
Laura Machin   +7 more
doaj   +1 more source

Synthesis of Bis(3‐indolyl)methanes Mediated by Potassium tert‐Butoxide

open access: yesChemistryOpen, 2023
The indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis(3‐indolyl)methanes (BIMs) are an important subgroup of indoles, composed
A. Sofia Santos   +5 more
doaj   +1 more source

Infrared Spectra of Small Radicals for Exoplanetary Spectroscopy: OH, NH, CN and CH: The State of Current Knowledge

open access: yesMolecules, 2023
In this study, we present a current state-of-the-art review of middle-to-near IR emission spectra of four simple astrophysically relevant molecular radicals—OH, NH, CN and CH.
Svatopluk Civiš   +4 more
doaj   +1 more source

Analysis of Protein Oxidative Modifications in Follicular Fluid from Fertile Women: Natural Versus Stimulated Cycles

open access: yesAntioxidants, 2018
Oxidative stress is associated with obstetric complications during ovarian hyperstimulation in women undergoing in vitro fertilization. The follicular fluid contains high levels of proteins, which are the main targets of free radicals.
Irantzu Pérez-Ruiz   +7 more
doaj   +1 more source

The reactivity of dopamine precursors and metabolites towards ABTS•-: An experimental and theoretical study [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
The antiradical activity of L-3,4-dihydroxyphenylalanine (L-DOPA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid and tyrosine towards 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt radical (ABTS-) was investigated ...
Dimić Dušan   +3 more
doaj   +1 more source

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