Results 11 to 20 of about 435,752 (317)
Setmelanotide – from genes to targeted therapy in some rare forms of obesity [PDF]
Obesity is a serious public health concern. It significantly affects an individual’s quality of life and is associated with an increased risk of developing other conditions, including diabetes, hypertension, and cardiovascular complications.
Dawid Frączkowski
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Zmarszczki i przebarwienia to widoczne skutki fotostarzenia skóry, którego mechanizmy omówiono pokrótce w poniżej pracy. Dotychczas do zwalczania jego skutków używano aplikowany miejscowo retinol, znany w dermatologii związek, stosowany z powodzeniem w ...
Mateusz Grzelecki +2 more
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The Modus Operandi of Hydrogen Sulfide(H2S)-Dependent Protein Persulfidation in Higher Plants
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function.
Francisco J. Corpas +4 more
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Antioxidant Activities of Hydroxylated Naphthalenes: The Role of Aryloxyl Radicals [PDF]
Herein is delineated a first systematic framework for the definition of structure-antioxidant property relationships in the dihydroxynaphthalene (DHN) series.
d'Ischia, Marco +7 more
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Radical Reactivity of Radical Ions in Solution. Radical--Radical and Radical--Substrate Coupling Mechanisms. [PDF]
The linear sweep voltammetry response to competitive radical ion-substrate coupling and radical ion dimerization mechanisms was determined by digital simulation. The simulations were carried out to mimic the conditions under which experimental studies had previously shown that the radical ion-substrate coupling mechanism is the preferred reaction ...
Vernon D. Parker +7 more
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Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)
α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985.
Jesper Bergwik +5 more
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A Review of Manganese(III) (Oxyhydr)Oxides Use in Advanced Oxidation Processes
The key role of trivalent manganese (Mn(III)) species in promoting sulfate radical-based advanced oxidation processes (SR-AOPs) has recently attracted increasing attention.
Daqing Jia +3 more
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Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells.
Laura Machin +7 more
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Synthesis of Bis(3‐indolyl)methanes Mediated by Potassium tert‐Butoxide
The indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis(3‐indolyl)methanes (BIMs) are an important subgroup of indoles, composed
A. Sofia Santos +5 more
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The radical ambitions of counter‐radicalization [PDF]
AbstractThe “Trojan Horse” scandal laid bare an anxiety at the heart of the British security establishment; an anxiety that brings together questions of identity, values, and security within the demand to manage radicalization. It is an anxiety that, I will argue, reveals a novel conceptualization of threat that has driven the UK’s security and ...
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