Results 41 to 50 of about 14,619 (258)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Review Article of Radio Frequency and Microwave Heating Treatment to Disinfest Kutu Beras in Malaysian Rice

MATEC Web of Conferences, 2017
This article presents the basic principle of radio frequency (RF) and microwave heating and its application in agricultural sector specifically to control rice insects for storage purpose.
Abdul Nyzam Siti Zulaika, Abd. Rahim Rosemizi, A. Rahim @ Samsuddin Hasliza   +2 more
doaj   +1 more source

Progress in stellarator research at IPP-Kharkov

Nukleonika, 2016
A new antenna of ‘crankshaft’ type has been installed in the Uragan-2M device in order to increase the plasma density and heating below the ion cyclotron frequency. Antenna operation is modelled by 1D code, which solves boundary problem for time-harmonic
Moiseenko Vladimir E., Lozin Oleksiy V., Shapoval Anatoliy M., Dreval Mykola B., Kulyk Yuliya S., Mironov Yuri K., Romanov Vladyslav S., Pashnev Valeriy K., Sorokovoy Eduard L., Petrushenya Andriy A., Ozherel’ev Fedir I., Kozulya Mykhailo M., Konovalov Volodymyr G., Maznichenko Sergiy M., Garkusha Igor E.   +14 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Ionosphere response to the impact of an extraordinary radio wave when located at a frequency close to the heating frequency

Solar-Terrestrial Physics
The paper presents the results of experiments on the impact of powerful high-frequency radio emission from the SURA mid-latitude heating facility (56.1° N, 46.1° E) on Earth's ionosphere.
Bahmetieva Nataliya, Grigoriev Gennadiy, Zhemyakov Ilia, Kalinina Elena, Lisov Aleksander   +4 more
doaj   +1 more source

Radar observations of artificial E-region field-aligned irregularities [PDF]

Annales Geophysicae, 2009
Artificial E region field aligned plasma density irregularities (FAIs) were generated using HAARP in four different experimental modes and observed with a coherent scatter radar imager located 450 km to the southwest where it could detect field ...
E. Nossa, D. L. Hysell, C. T. Fallen, B. J. Watkins   +3 more
doaj   +1 more source