Results 71 to 80 of about 27,791 (256)

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Simultaneous dislocation of the radial head and distal radio-ulnar joint. A case report

open access: yesInternational Journal of Medical Sciences, 2008
Isolated dislocation of the distal radio-ulnar joint and isolated dislocation of the radial head in adults are not common injuries. A simultaneous dislocation of the radial head and distal radio-ulnar joint with no other injury seems to be extremely rare
D-A.J. Verettas, G.I. Drosos, K.C. Xarchas, C.N. Chatzipapas, C. Staikos
doaj  

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Lesiones del carpo asociadas a fracturas del radio distal: correlación artroscópicotomográfica

open access: yesRevista de la Asociación Argentina de Ortopedia y Traumatología
Introducción: La fractura del radio distal representa una de las fracturas más frecuentes. La prevalencia de lesiones intercarpianas asociadas llega al 70%.
Agustina Laboranti   +9 more
doaj   +1 more source

Resultados funcionais e radiológicos a longo prazo da fixação percutânea das fraturas da extremidade distal do rádio Distal radius fractures: long term functional and radiological results of percutaneous pinning fixation

open access: yesRevista Brasileira de Ortopedia, 2012
OBJETIVO: O objetivo do presente estudo é a análise funcional e radiográfica, a longo prazo, dos pacientes com fratura do rádio distal tratados com redução fechada e fixação percutânea com fios de Kirschner.
Arlindo Gomes Pardini Júnior   +3 more
doaj   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

open access: yesAdvanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

COMBINED PLATE VERSUS EXTERNAL FIXATION FOR DISTAL RADIUS FRACTURES. [PDF]

open access: yesActa Ortop Bras, 2023
Polat O, Toy S, Özbay H.
europepmc   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

Fixação das fraturas da extremidade distal do rádio pela técnica de kapandji modificada: avaliação dos resultados radiológicos Fixation of fractures of the distal extremity of the radius using the modified kapandji technique: evaluation of the radiological results

open access: yesRevista Brasileira de Ortopedia, 2011
OBJETIVO: Demonstrar uma opção simples e eficaz para o tratamento das fraturas da extremidade distal do rádio com o uso de fios de Kirschner. MÉTODOS: No período de setembro de 2008 a abril de 2009, foram tratados, cirurgicamente, 48 pacientes com ...
Antonio Piva Neto, Fabio Colla Lhamby
doaj   +1 more source

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