Results 81 to 90 of about 4,766,380 (340)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

AN ARECIBO SEARCH FOR PULSARS AND TRANSIENT SOURCES IN M33 [PDF]

, 2011
We report on a systematic and sensitive search for pulsars and transient sources in the nearby spiral galaxy M33, conducted at 1.4 GHz with the Arecibo telescope's seven-beam receiver system, ALFA.
N. D. Bhat, J. Cordes, P. Cox, J. Deneva, T. Hankins, T. J. Lazio, M. McLaughlin   +6 more
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

An Extremely Active Repeating Fast Radio Burst Source in a Likely Nonmagneto-ionic Environment

The Astrophysical Journal
Fast radio bursts (FRBs) are bright radio bursts originating at cosmological distances. Only three repeating FRBs FRB 20121102A, FRB 20190520B, and FRB 20201124A among ∼60 known repeating FRBs have circular polarization.
Yi Feng, Di Li, Yong-Kun Zhang, Chao-Wei Tsai, Yuanhong Qu, Wei-Yang Wang, Yuan-Pei Yang, Pei Wang, Dengke Zhou, Jiarui Niu, Chenchen Miao, Mao Yuan, Jiaying Xu, Ryan S. Lynch, William Paul Armentrout, Brenne Gregory, Lingqi Meng, Shen Wang, Xianglei Chen, Shi Dai, Chen-Hui Niu, Mengyao Xue, Ju-Mei Yao, Bing Zhang, Junshuo Zhang, Weiwei Zhu, Jintao Xie, Yuhao Zhu   +27 more
doaj   +1 more source

Zooming-in on the sources of fast radio transients

, 2022
Since the 1960s, Galactic neutron stars have been known to emit short duration radio transients. More recently, a population of higher luminosity short-duration radio transients originating from extragalactic distances were discovered. The nature of these fast radio bursts (FRBs) still remains a mystery, but it is clear that they reflect an extreme ...
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Comprehensive Study of the Energy and Redshift Distributions of the Fast Radio Burst Population Based on the First CHIME/FRB Catalog

The Astrophysical Journal
Fast radio bursts (FRBs) are brief, high-energy bursts of radio waves from extragalactic sources, and their origin remains an open question. In this paper, we perform a comprehensive analysis of the FRB population using the first CHIME/FRB catalog ...
Qing-Zhen Lei, Xin-Zhe Wang, Can-Min Deng   +2 more
doaj   +1 more source

MULTIMOMENT RADIO TRANSIENT DETECTION [PDF]

, 2011
We present a multimoment technique for signal classification and apply it to the detection of fast radio transients in incoherently dedispersed data. Specifically, we define a spectral modulation index in terms of the fractional variation in intensity ...
L. Spitler, J. Cordes, S. Chatterjee, J. Stone   +3 more
semanticscholar   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Modeling Current and Future High-cadence Surveys of Repeating Fast Radio Burst Populations

The Astrophysical Journal
In recent years, the Canadian Hydrogen Intensity Mapping Experiment (CHIME) interferometer has revealed a large number of fast radio bursts (FRBs), including a sizable population that demonstrates repeating behavior.
Kyle McGregor, Duncan R. Lorimer
doaj   +1 more source