Results 131 to 140 of about 398,650 (328)
Advanced Science, EarlyView.Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra +9 more
wiley +1 more source
BJS (British Journal of Surgery), EarlyView., 2020 This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund +4 more
wiley +1 more source
\u3csup\u3e99m\u3c/sup\u3eTc-Labeled C2A Domain of Synaptotagmin I as a Target-Specific Molecular Probe for Noninvasive Imaging of Acute Myocardial Infarction [PDF]
, 2006 : The exposure of phosphatidylserine (PtdS) is a common molecular marker for both apoptosis and necrosis and enables the simultaneous detection of these distinct modes of cell death. Our aim was to develop a radiotracer based on the PtdS-binding activity
Fang, Wei +7 more
core +1 more source
A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate
Advanced Science, EarlyView.Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao +12 more
wiley +1 more source
Induced radioactivity in LDEF components [PDF]
A systematic study of the induced radioactivity of the Long Duration Exposure Facility (LDEF) is being carried out in order to gather information about the low earth orbit radiation environment and its effects on materials.
Fishman, G. J. +3 more
core +1 more source
Advanced Science, EarlyView.Undesirable phase transition behavior and anti‐disproportionation performance limit the hydrogen isotope storage of Zr2Fe alloy. With theoretical screening and experiments, partial Cu/Ni substitutions achieve full reversibility and significantly improve anti‐disproportionation properties.
Zhiyi Yang +12 more
wiley +1 more source
Radioactivity in returned lunar materials [PDF]
The H-3, Ar-37, and Ar-39 radioactivities were measured at several depths in the large documented lunar rocks 14321 and 15555. The comparison of the Ar-37 activities from similar locations in rocks 12002, 14321, and 15555 gives direct measures of the ...
core +1 more source