Results 61 to 70 of about 25,870 (184)

radiochemical separation

, 2014
Citation: 'radiochemical separation' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05097 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +1 more source

radiochemical purity

, 2014
Citation: 'radiochemical purity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05096 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Fully-automated radiosynthesis of the amyloid tracer [11C] PiB via direct [11C]CO2 fixation-reduction

EJNMMI Radiopharmacy and Chemistry, 2019
Background The β-amyloid radiotracer [11C] PiB is extensively used for the Positron Emission Tomography (PET) diagnosis of Alzheimer’s Disease and related dementias.
Pablo Buccino, Eduardo Savio, Williams Porcal   +2 more
doaj   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Automated Synthesis of 5-HT1A Receptors Antagonists 11C-WAY-100635

Journal of Isotopes, 2017
A fully automated synthesis of 11C-labeled-N-［2-［4-(2-methoxyphenyl)-1-piperazinyl］ethyl］-N-2-pyridinylcyclohexanecarboxamide maleate (11C-WAY-100635) for imaging 5-HT1A receptors was performed on a module system.
LI Hui-qiang1,2;ZHEN Zhi-fei1;ZHANG Wei-feng1;LIAO Shu-guang1;LI Hong-li3;XU Jun-ling1,2
doaj   +1 more source

Physicochemical and Biological Analysis of 99mTc-Glutathione Radiopharmaceuticals

Atom Indonesia, 2013
99mTc-glutation (99mTc-GSH) radiopharmaceutical is available in the GSH lyophilized-kit in which ready to use directly after adding 99mTc radionuclide.
M.E. Sriyani, N. Zainuddin
doaj  

QUALITY CONTROL OF RADIOPHARMACEUTICALS IN MEDICAL INSTITUTIONS

Разработка и регистрация лекарственных средств, 2019
One of the major nuclear medicine agent is radiopharmaceutical (RPh) which is a composition comprising a radioactive isotope in certain chemical form. Quality control, namely the determination of radiochemical purity of radiopharmaceuticals produced in a
G. E. Kodina, A. O. Malysheva
doaj  

First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [F]T807

Molecular Imaging, 2014
Despite extensive preclinical imaging with radiotracers developed by continuous-flow microfluidics, a positron emission tomographic (PET) radiopharmaceutical has not been reported for human imaging studies by this technology.
Steven H. Liang, Daniel L. Yokell, Marc D. Normandin, Peter A. Rice, Raul N. Jackson, Timothy M. Shoup, Thomas J. Brady, Georges El Fakhri, Thomas L. Collier, Neil Vasdev   +9 more
doaj   +1 more source

Automated Scale-Down Development and Optimization of [⁶⁸Ga]Ga-DOTA-EMP-100 for Non-Invasive PET Imaging and Targeted Radioligand Therapy of c-MET Overactivation in Cancer

Biologics
Background/Objectives: Overactivation of the HGF/c-MET pathway is implicated in various cancers, making its inhibition a promising therapeutic strategy.
Silvia Migliari, Anna Gagliardi, Alessandra Guercio, Maura Scarlattei, Giorgio Baldari, Alex Gibson, Christophe Portal, Livia Ruffini   +7 more
doaj   +1 more source

radiochemical purification

, 2014
Citation: 'radiochemical purification' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05095 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source