Results 51 to 60 of about 25,870 (184)

Correspondence of Basal Forebrain Resting‐State Functional Connectivity and Cerebral Glucose Metabolism Alterations With Neurotransmitter Maps in Alzheimer's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Altered functional connectivity of basal forebrain subregions (Ch1‐3, Ch4) and widespread cerebral hypometabolism were identified in Alzheimer's disease using simultaneous PET/MRI. Spatial correspondence with normative neurotransmitter receptor and transporter maps suggested that serotonergic and dopaminergic systems may contribute to AD‐related ...
Yujie He, Hanxiao Xue, Sheng Bi, Yan Wang, Xiaocao Liu, Yixia Li, Zhigeng Chen, Dongdong Rong, Bixiao Cui, Jie Ma, Shaozhen Yan, Jie Lu   +11 more
wiley   +1 more source

A comparison of radiochemical purity testing of 99m Tc-Pentetate (DTPA) between paper and thin layer chromatographic techniques

Journal of Associated Medical Sciences, 2016
Introduction: 99mTc-Pentetate or 99mTc-DTPA (99mTc-diethylenetriaminepentaacetic acid) is radiopharmaceutical material for renal function study in nuclear medicine.
Montree Tungjai, Thitima Yingyai, Tarika Thumvijit   +2 more
doaj  

The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method [PDF]

Journal of Pure and Applied Chemistry Research, 2021
Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown.
Amal Rezka Putra, Khoirunnisa Fauziah Asyikin, Robertus Dwi Hendarto, Agus Ariyanto, Enny Lestari, Sumandi Juliyanto, Ahsanal Fikri   +6 more
doaj  

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

Journal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta, Manoj Kumar, Krishna Mohan Repaka, Amit Das, Ajit A. Kengar, Drishty Satpati   +5 more
wiley   +1 more source

Safety of [68Ga]Ga‐FAPI‐46 PET/CT including hemodynamic measurements and patient‐reported outcomes in cancer patients

Clinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.
Abstract Introduction Aim Fibroblast activation protein inhibitor (FAPI) has demonstrated promising oncological diagnostic performance. Although no adverse events (AEs) have been previously reported, a formal safety evaluation of FAPI PET/CT is lacking.
Morten Bentestuen, Camilla Sylvest, Svend B. Jensen, Lara R. Soro, Aage Knudsen, Morten Ladekarl, Ole Thorlacius‐Ussing, Wolfgang P. Fendler, Helle D. Zacho   +8 more
wiley   +1 more source

Development and Validation of a Radiochemical Purity Determination Method for [68Ga]Ga-DOTA-CXCR4-D1

Journal of Isotopes
CXCR4 is a chemokine receptor widely overexpressed on the surface of various tumor cells. Given its pivotal role in tumor invasion，metastasis，and recurrence，it has emerged as a key target in molecular imaging.
Jingjing YU, Xiaoming WANG, Houquan LI, Xu ZHOU, Hongyu LI, Yang PEI, Xiangyu QIN, Kai WEN, Guobao WANG   +8 more
doaj   +1 more source

Ryugu reference project: Recommendations from the measurement definition team

Meteoritics &Planetary Science, Volume 61, Issue 5, Page 819-848, May 2026.
Abstract Sample return missions play a significant role in planetary science by providing pristine extraterrestrial materials. JAXA's Hayabusa2 and NASA's OSIRIS‐REx missions have returned samples from the C‐type asteroids Ryugu and Bennu, respectively. The chemical and mineralogical compositions of these samples closely resemble those of CI chondrites,
Tetsuya Yokoyama, Guillaume Avice, Henner Busemann, Nicolas Dauphas, Daniel P. Glavin, Ashley J. King, Thorsten Kleine, Katharina Lodders, Frederic Moynier, Maria Schönbächler, Yoshinori Takano, Kun Wang, Hikaru Yabuta, Yuma Enokido, Ryota Fukai, Shogo Tachibana, Tomohiro Usui   +16 more
wiley   +1 more source

Dynamic Flow Approaches for Automated Radiochemical Analysis in Environmental, Nuclear and Medical Applications

Molecules, 2020
Automated sample processing techniques are desirable in radiochemical analysis for environmental radioactivity monitoring, nuclear emergency preparedness, nuclear waste characterization and management during operation and decommissioning of nuclear ...
Jixin Qiao
doaj   +1 more source

Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors

Beilstein Journal of Organic Chemistry, 2017
Continuous-flow microfluidics has shown increased applications in radiochemistry over the last decade, particularly for both pre-clinical and clinical production of fluorine-18 labeled radiotracers.
Thomas Lee Collier, Steven H. Liang, J. John Mann, Neil Vasdev, J. S. Dileep Kumar   +4 more
doaj   +1 more source

Iodine-131 labeled genistein as a potential radiotracer for breast cancer

Heliyon, 2020
Objective: Genistein is an isoflavone compound that has been proven to have anticancer activity and is capable of binding to estrogen β receptors with Selective Estrogen Receptor Modulators (SERMs) properties, and has a strong affinity to inhibit the ...
Danni Ramdhani, Eva Maria Widyasari, Maula Eka Sriyani, Quinzheilla Putri Arnanda, Hiroshi Watabe   +4 more
doaj   +1 more source