Results 101 to 110 of about 16,167 (209)

Cost-effective quality control method for radiochemical purity of 99m Tc-Tectrotyd used in a Hospital Radiopharmacy unit

, 2021
The new Radiopharmacy in Nuclear Medicine department in the Hospital and University Service of Kosovo apply the policy that all products administered into the human body, especially the new one are safe and show a constant high quality in producing the ...
Makraduli, Liljana, Grozdanovska, Jasna, Janevik-Ivanovska, Emilija, Jashari, Armend, Adzi-Andov, Ljubica, Kaçiu, Yll   +5 more
core  

Simultaneous measurements of the molar radioactivity, radiochemical purity and chemical impurity in the [11C]choline injection using radio-HPLC with a corona-charged aerosol detector.

, 2020
[11C]choline has a weak UV absorption chromophore, and it is challenging to detect less than 1 μg/mL choline using radio-HPLC-UV. In this study, we established an analytical procedure of [11C]choline using the radio- HPLC coupled with the corona-charged ...
866603, 866614, Hashimoto, Hiroki, Kawamura, Kazunori, 866613, 866605, Ming-Rong, Zhang, 866616, Furutsuka, Kenji, 866604, 866615, 866607, 866618, 866606, 866617, 866609, 866608, Kurihara, Yusuke, Ohkubo, Takayuki, Nengaki, Nobuki, 866610, 866612, Ogawa, Masanao, 866611   +23 more
core   +1 more source

Design and radiosynthesis of class-IIa HDAC inhibitor with high molar activity via repositioning the 18F-radiolabel

Scientific Reports
The design and radiosynthesis of [18F]NT376, a high potency inhibitor of class-IIa histone deacetylases (HDAC) is reported. We utilized a three-step radiochemical approach that led to the radiosynthesis of [18F]NT376 in a good radiochemical yield, (17.0 ±
Sulan Xu, Chun-Han Huang, Christopher Eyermann, Georgios V. Georgakis, Nashaat Turkman   +4 more
doaj   +1 more source

Determination of radiochemical purity of radiopharmaceuticals TechneScan HDP by chromatography using different mobile and stationary phases

, 2013
Nuclear medicine is a relatively young medical field. The nuclear medicine department performs both diagnostic tests and therapies using open radiation sources whereas the diagnostic use currently prevails.
RAUS, Klára
core  

Development and Validation of a GMP-Compliant High-Pressure Liquid Chromatography Method for the Determination of the Chemical and Radiochemical Purity of [¹⁸F]PSMA-1007, a PET Tracer for the Imaging of Prostate Cancer. [PDF]

Pharmaceuticals (Basel), 2021
Katzschmann I, Marx H, Kopka K, Hennrich U.   +3 more
europepmc   +1 more source

Evaluation radiochemical purity of 177lu-labelled Rituximab conjugates using HPLC method

, 2014
In the field of radiolabelled molecules, Rituximab appear as promising molecules for radiopharmaceutical design, because it can target specifically to antigensin non-Hodgkin lymphoma.
Janevik-Ivanovska, Emilija, Smilkov, Katarina, Gjorgieva Ackova, Darinka, Carollo, Angela, Chinol, Marco, Arev, Marija   +5 more
core  

Preparation of -macroaggregated albumin for lung perfusion studies

Nucleus, 2009
The present paper shows the design, optimization, quality control for testing radiochemical purity, biological quality and realtime stability studies of a preparation of macroaggregated albumin from the controlled denaturation of HSA.
Yumisley Alfonso Marín, Alejandro Rivero Santamaría, Ignacio Hernández González   +2 more
doaj  

The simultaneous measurement method for the molar radioactivity, radiochemical purity, and chemical impurity of the [11C]choline injection

, 2018
Background/Aims: [11C]Choline has been extensively used clinically for imaging prostate cancer [1]. [11C]Choline is prepared by 11C-methylation of [11C]methyl iodide and 2-dimethylaminoethanol (DMAE).
Hashimoto, Hiroki, Kawamura, Kazunori, Furutsuka, Kenji, 716738, 716739, Kariya, Kaori, 狩谷 香, 河村 和紀, 716740, 橋本 裕輝, Zhang, Ming-Rong, 古塚 賢士, 張 明栄, 716736, Nengaki, Nobuki, 716737, 716734, 716735, 716732, 念垣 信樹, 716733, 716741, 716731, 716742   +23 more
core  

Synthesis and Preliminary Biological Evaluation of 68Ga-labeled GIPR Targeting Probe

Journal of Isotopes
Glucose-dependent insulinotropic polypeptide receptor (GIPR) is one of the important targets of neuroendocrine tumors (NETs). In this study，a novel GIPR targeting probe 68Ga-DOTA-GIP(1-30)-F-02 was constructed through the module for automatic labeling ...
Pengjun ZHANG, Jiang WU, Bo LUO, Wenyu WU, Feng WANG   +4 more
doaj   +1 more source

A radio-high-performance liquid chromatography dual-flow cell gamma-detection system for on-line radiochemical purity and labeling efficiency determination

, 2014
In this study, a method of determining radiochemical yield and radiochemical purity using radio-HPLC detection employing a dual-flow-cell system is evaluated. The dual-flow cell, consisting of a reference cell and an analytical cell, was constructed from
Jacobsson, Lars,, Lindegren, Sture,, Jensen, Holger   +2 more
core   +1 more source