Results 81 to 90 of about 16,167 (209)

Development of ready to use kit formulation for trastuzumab radioimmunoconjugates and identification of radiochemical purity as the first step in quality control of the final product [PDF]

, 2022
Aim The aim of this study is to present the part of our project dedicated to obtaining a stable, ready to use freeze dried kit formulation of antibody radioimmunoconjugates (trastuzumab immunoconjugates labelled with 90Y and 177Lu). As the first step in
Janevik-Ivanovska, Emilija, Mirkovic, Marija, Radovic, Magdalena, Vranjes-Duric, Sanja, Jankovic, Drina, Arev, Marija, Apostolova, Paulina   +6 more
core  

Absorbed Dose of Human Organs after Injection of 68Ga-EDTMP: Estimation from Biodistribution Data in Wild-Type Rats

Frontiers in Biomedical Technologies, 2018
Purpose: 68Ga is a generator-based radionuclide with suitable characteristics for PET imaging. 68Ga-EDTMP has recently been introduced as a new agent for bone imaging. In this study, the human absorbed dose of this agent was calculated according to RADAR
Hassan Yousefnia, Samaneh Zolghadri, Amir Reza Jalilian   +2 more
doaj  

Preliminary Study of Radioiodination of VP2

Journal of Isotopes, 2016
The VP2 peptide specifically binding to vasoactive intestinal polypeptide receptor 1(VPAC1) receptor was radioiodinated with 131I by bi-functional linker N-succinimidyl 5-(tributylstannyl)-3-pyridinecarboxylate (SPC), and in vitro and in vivo stability ...
MA Huan, TANG Yu, YANG Yuan-you, LIU Ning, LIAO Jia-li, YANG Ji-jun   +5 more
doaj   +1 more source

Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer

Small, Volume 22, Issue 35, 23 June 2026.
Fluorination of a self‐assembling dendrimer nanosystem reduced liver retention, accelerated renal clearance and improved biodistribution, ultimately enhancing tumor uptake and enabling more sensitive tumor detection by positron emission tomography (PET).
Béatrice Louis, Tom Roussel, Twiany Cruz‐Dubois, Ling Ding, Zhenbin Lyu, Erik Laurini, Jessica Ou, Laure Balasse, Adrien Chabert, Vincent Nail, Ahlem Bouhlel, Françoise Dignat‐George, Florence Gattacceca, Sabrina Pricl, Benjamin Guillet, Ling Peng, Philippe Garrigue   +16 more
wiley   +1 more source

The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells

Drug Delivery, 2020
The aim of current study is to develop new nanostructured lipid carrier systems (NLCSs) containing imatinib mesylate (IMT) and evaluate their targeting efficiency on NIH-3T3 as fibroblast cells and CRL-1739 as gastric adenocarcinoma cells with ...
Evren Atlihan Gundogdu, Emine Selin Demir, Meliha Ekinci, Emre Ozgenc, Derya Ilem Ozdemir, Zeynep Senyigit, Makbule Asikoglu   +6 more
doaj   +1 more source

Nanobodies: A Promising Toolkit for Diagnostic Applications

SmartMat, Volume 7, Issue 3, June 2026.
This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu, Abid Ali, Li Sun, Jiahao Hu, Lina Hameed, Saba Shafi, Ali Raza, Khuzin Dinislam, Wenjing Xing, Long Rong, Jie Lin, Jian Ma   +11 more
wiley   +1 more source

Comparison of radiochemical yields obtained with native or 2-IT derivatized IgG, depending on IgG amount.

, 2015
Radiochemical purity (RCP) were performed by ITLC-SG/NaCl 0,9%.
Isabelle Quelven (803908), Hélène Carpenet (803906), Jacques Monteil (803907), Armelle Cuvillier (40496)   +3 more
core   +1 more source

OsFKBP20‐1b stabilizes OsUPF1 and OsUPF2 to promote the degradation of aberrant mRNAs during dehydration stress

Journal of Integrative Plant Biology, Volume 68, Issue 6, Page 1672-1691, June 2026.
The rice protein OsFKBP20‐1b protects key RNA‐surveillance factors from breakdown, so they can better eliminate defective messages. This RNA quality‐control boost reduces errors and helps plants survive drought, revealing a link between RNA control and drought tolerance.
Haemyeong Jung, Hyun Ji Park, Seung Hee Jo, Ki‐Hong Jung, Choonkyun Jung, Hye Sun Cho   +5 more
wiley   +1 more source

Radiochemical Purity of 68Ga-BCA-Peptides: Separation of All 68Ga Species with a Single iTLC Strip

, 2016
In the present study, highly effective iTLC single strip method for the determination of radiochemical purity (RCP) of 68Ga-BCA-peptides was developed (with no double-developing, changing of eluents or other additional manipulation).
Alesya Ya Maruk, Anton A. Larenkov
core   +1 more source

Production of 211At and automated radiosynthesis of [211At]MABG via electrophilic astatodesilylation

EJNMMI Radiopharmacy and Chemistry
Background [211At]m-Astatobenzylguanidine ([211At]MABG) has demonstrated potent antitumor efficacy in preclinical models of malignant neuroendocrine tumours including neuroblastoma and pheochromocytoma/paraganglioma.
Yuto Kondo, Taiki Joho, Shigenori Sasaki, Kazumasa Mochizuki, Naoko Hasegawa, Naoyuki Ukon, Ken-ichi Nishijima, Kohshin Washiyama, Hiroshi Tanaka, Tatsuya Higashi, Noriko S. Ishioka, Kazuhiro Takahashi   +11 more
doaj   +1 more source