Results 71 to 80 of about 16,167 (209)

Determination of radiochemical purity and stability of new radiopharmaceuticals

, 2010
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Nikola Vorlová Supervisor: Prof. PharmDr. Ing. Milan Lázniček, CSc.
Vorlová, Nikola
core  

Technetium-99m-labeled genistein as a potential radical scavenging agent

Journal of Advanced Pharmaceutical Technology & Research, 2019
The purpose of this study was to determine the optimum conditions for labeling genistein compounds with technetium-99m (99mTc) radionuclides and the percentage of purity obtained in accordance with the requirements of the United State Pharmacopeia.
Danni Ramdhani, Maula Eka Sriyani, Flamboyan Ayu   +2 more
doaj   +1 more source

Prognostic and Predict Value of Peripheral Blood Circulating Tumor Cells Programmed Death‐Ligand 1 Expression and F‐18‐Fluorodeoxyglucose Metabolic Parameters in Patients With Advanced Non‐Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Purpose To investigate the concordance and correlation between programmed death‐ligand 1 (PD‐L1) expression in tumor tissue and circulating tumor cells (CTCs), explore the intrinsic link between epithelial‐mesenchymal transition (EMT) and PD‐L1 expression in CTCs, and examine the predictive value of FDG metabolic parameters, CTCs and their PD ...
Momo Sun, Aisikaer Aikedan, Zhongying Rui, Enci Ding, Jie Shen   +4 more
wiley   +1 more source

Optimal 18F-fluorination conditions for the high radiochemical yield of [18F]AlF-NOTA-NHS complexes

, 2021
18F-fluorination using aluminum-fluoride ([18F]AlF) chelate technique has been reported to give a low-to-moderate radiochemical yield, between 5 and 20%. Therefore, the work described here outlines the optimum 18F-fluorination condition for the formation
Abdul Razak, Hairil Rashmizal, Hassan, Hishar, Othman, Muhammad Faiz   +2 more
core   +1 more source

Termination of Carbomethoxyethyl Radicals Generated by Br‐Atom Abstraction From MeCH(Br)COOMe With Metalloradicals: Implications for Polyacrylate Radical Termination

ChemistryEurope, Volume 4, Issue 6, June 2026.
Combination is the dominant bimolecular termination mode of the diffused acrylate radical carbomethoxyethyl (MeCH•(COOMe), or RH•), but its generation by Br‐atom abstraction from methyl 2‐bromopropionate (RH‐Br) with a variety of metalloradicals (Mt•) opens a competitive pathway via the {RH•, Mt•} caged pair, leading to 100% disproportionation ...
Laurianne Forget, Christophe Fliedel, Krzysztof Matyjaszewski, Rinaldo Poli   +3 more
wiley   +1 more source

Preparation and Quality Control of 68Ga-Citrate for PET Applications [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2015
Objective(s): In nuclear medicine studies, gallium-68 (68Ga) citrate has been recently known as a suitable infection agent in positron emission tomography (PET).
Ayuob Aghanejad, Amir Jalilian, Khosro Ardaneh, Fatemeh Bolourinovin, Hassan Yousefnia, Ali Bahrami-Samani   +5 more
doaj  

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Determination of radiochemical purity of radiomercury by paper chromatography

BUNSEKI KAGAKU, 1974
放射性第二水銀製品溶液中の第一水銀,第二水銀および不純物として含まれる銀イオンの定量のためにペーパークロマトグラフ法による純度検定法を確立した.第一水銀,第二水銀の展開分離においては溶媒として,酢酸:硝酸:水の比が150:3:5のものを使用して展開した結果,Rf値がそれぞれ0.14,0,49であった.この溶媒では銀イオンと第一水銀イオンが同じ位置にあり両者を分離するためには,酢酸:硝酸:水の比が15:1:4の溶媒で展開した.その結果,銀イオン,第一水銀イオン,第二水銀イオンのRf値がそれぞれ0.52,0.73,0.79であり,銀イオンと水銀イオンの分離が可能であった.したがって上記2種類の溶媒でそれぞれ展開することにより第一水銀,第二水銀,銀の分離定量が可能である ...
EBIHARA, Hiroshi, KAMIOKI, Hiroshi
openaire   +2 more sources

Synthesis and Evaluation of 99mTc Essential Analogue of DUPA PSMA Inhibitor for Its Potential Use in Prostate Cancer Imaging

ChemistrySelect, Volume 11, Issue 21, 4 June 2026.
ABSTRACT DUPA (2‐[3‐(1,3‐dicarboxy propyl) ureido] pentanedioic acid) is a known small molecule prostate‐specific membrane antigen (PSMA) enzyme inhibitor that targets the PSMA receptor found overexpressed on prostate cancer. The present work synthesizes and evaluates a 99mTc (technetium) “metal essential” glutamate complex, which mimics the DUPA ...
Navin Sakhare, Sheela Muralidharan, Dheeraj Kumar, Shubhankar Dutta, Rani Gnanasekar, Shalaka Paradkar, Arpit Mitra, Bhabani Mohanty, Shubhangi Mirapurkar, Anupam Mathur, Pradip R. Chaudhari, Kakoli Bose   +11 more
wiley   +1 more source

Drug composition matters: the influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP

, 2015
Item does not contain fulltextINTRODUCTION: (188)Rhenium-HEDP is an effective bone-targeting therapeutic radiopharmaceutical, for treatment of osteoblastic bone metastases.
van der Westerlaken, M.M.L., Bloemendal, H. J., Klerk, J.M. de, Beekman, F. J., Bloemendal, H.J., ter Heine, R., Westerlaken, M.M. van der, de Klerk, J.M.H., Hendrikse, N. H., Lange, R., Ramakers, R.M., Ramakers, R. M., Beekman, F.J., de Klerk, J. M H, Heine, R. ter, van der Westerlaken, M. M L, Hendrikse, N.H.   +16 more
core   +1 more source