Results 51 to 60 of about 186,978 (199)

Context‐Dependent Radioenhancement by Platinum Nanoparticles Under Conventional and Ultra‐High Dose‐Rate “FLASH” Radiotherapy

Small, EarlyView.
Overview of the experimental workflow and main findings of the study investigating Pt‐NPs‐mediated radioenhancement under conventional 134 dose‐rate (CONV) and ultrahigh dose‐rate (UHDR) 9 MeV electron irradiation. Pt‐NP distribution and uptake were characterized in 4T1 spheroids and syngeneic tumor models.
Cathyanne Schott, Foutina Feghali, Marine Gerbé de Thoré, Amina Joudat, Lydia Meziani, Aashini Rajpal, Winchygn Liu, Tudor Manoliu, Farah Savina, Sandrine Lacombe, Eric Deutsch, Julie Colnot, Charlotte Robert, Erika Porcel, Pauline Maury   +14 more
wiley   +1 more source

An HPLC and UHPLC-HRMS approach to study PSMA-11 instability in aqueous solution

EJNMMI Radiopharmacy and Chemistry, 2021
Background The stability of precursors and reagents is of utmost importance for developing a robust radiolabelling method that provides high and constant radiochemical yield and radiochemical purity.
Antonella Iudicello, Filippo Genovese, Valentina Di Iorio, Gianfranco Cicoria, Stefano Boschi   +4 more
doaj   +1 more source

A DPP6‐Targeted PET Tracer for Non‐Invasive Imaging of Transplanted Human Islets

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Dipeptidyl peptidase‐like protein 6 (DPP6) is a potential molecular imaging biomarker for pancreatic and transplanted islets of Langerhans. 4hD29 is a single‐domain antibody with nanomolar affinity for DPP6. Here, we demonstrate the generation and validation of [68Ga]Ga‐NOTA‐4hD29 for Positron Emission Tomography (PET) imaging of ...
Amina Khalil, Arturo Roca‐Rivada, Svitlana Vasylovska, Lorenzo J. I. Balestri, Irina Velikyan, Sayro Jawurek, Alexandra C. Title, Burcak Yesildag, Luke R. Odell, Joey Lau, Decio L. Eizirik, Olof Eriksson   +11 more
wiley   +1 more source

Percent radiochemical purity of [^99mTc]MBT2 and [^99mTc]BT2 as a function of time.

, 2016
Percent radiochemical purity of [99mTc]MBT2 and [99mTc]BT2 as a function of time.
Hiroyuki Watanabe (312793), Masashi Yoshimura (328061), Masafumi Ihara (302200), Masahiro Ono (106488), Shimpei Iikuni (458368), Hatsue Ishibashi-Ueda (781355), Hideo Saji (458369)   +6 more
core   +1 more source

Radiochemical purity and stability of 99mTc-HMPAO in routine preparations

, 2017
The aim of this work was to investigate the influence of pH, recovery volume, type of saline solution plastic or glass container, used to prepare the technetium-99m-d,l-hexamethylpropyleneamineoxime ([Tc-99m]Tc-d,l-HMPAO] radiopharmaceutical starting ...
Alessandra Boschi, PASQUALI, Micol, UCCELLI, Licia, Micol Pasquali, BOSCHI, Alessandra, Petra Martini, Licia Uccelli, MARTINI, Petra   +7 more
core   +1 more source

Physicochemical and Biological Analysis of 99mTc-Glutathione Radiopharmaceuticals

Atom Indonesia, 2013
99mTc-glutation (99mTc-GSH) radiopharmaceutical is available in the GSH lyophilized-kit in which ready to use directly after adding 99mTc radionuclide.
M.E. Sriyani, N. Zainuddin
doaj  

Automated Scale-Down Development and Optimization of [⁶⁸Ga]Ga-DOTA-EMP-100 for Non-Invasive PET Imaging and Targeted Radioligand Therapy of c-MET Overactivation in Cancer

Biologics
Background/Objectives: Overactivation of the HGF/c-MET pathway is implicated in various cancers, making its inhibition a promising therapeutic strategy.
Silvia Migliari, Anna Gagliardi, Alessandra Guercio, Maura Scarlattei, Giorgio Baldari, Alex Gibson, Christophe Portal, Livia Ruffini   +7 more
doaj   +1 more source

Determination of Radiochemical Purity and Pharmacokinetic Parameters of 99mTc-Sulphur Colloid and 99mTc-Tin Colloid

, 1981
Labelling yield and radiochemical purity, higher than 95%, of 99mTc-colloid preparations were determined by using the paper chromatography method. Less than 3% of labelled citric acid, added to the preparation as a buffer solution, has been found in ...
D. Konstantinovska, K. Milivojević, J. Bzenić, V. Jovanović   +3 more
core   +1 more source

In Situ Self‐Assembled Molecular Fortifying Agent for Enhanced Retention and Therapeutic Efficacy of Radiopharmaceuticals

Aggregate, Volume 7, Issue 10, October 2026.
A molecular‐fortifying agent strategy based on in situ self‐assembly is developed to prolong tumor retention of radioligands. After tumor‐targeting, FAP‐α cleavage triggers nanofiber formation, presenting azide anchors for bioorthogonal capture of pre‐accumulated radioligands.
Daojia Liu, Xiaoqin Luo, Xiaojuan Wang, Xing Liu, Fanglei Zhang, Pan Wang, Jibin Song, Junqiang Chen   +7 more
wiley   +1 more source

Morality, Colour, Bodies: Epistemological and Interpretive Questions of Purity [PDF]

, 2013
As contributors to this special edition show in different ways, purity itself is a less stable concept than may first appear. This insight, however, is not always reflected in dominant theory on the topic.
Robson, Ian, Duschinsky, Robbie
core