Results 31 to 40 of about 16,167 (209)

Validation of Hplc Method for the Determination of Chemical and Radiochemical Purity of a 68ga-Labelled Euk-Sub Dotaga

, 2021
The prostate-specific membrane antigen (PSMA) represents an ideal biomarker for molecular imaging. Various PSMA-targeted radioligands are available for prostate cancer imaging.
ELÇİ, ŞÜKRÜ GÖKHAN, Elçi, Ş.G., Yuksel, Doganguen, Uğur, A., Yüksel, D., Ugur, Ayse   +5 more
core   +1 more source

A Rapid Radiochemical Purity Testing Method for 99mTc-Tetrofosmin [PDF]

Journal of Nuclear Medicine Technology, 2010
The standard radiochemical purity (RCP) testing method for (99m)Tc-tetrofosmin as described in the package insert requires extensive time (20-30 min) and considerable skill to achieve accurate results. Additionally, the instant thin-layer chromatography strip impregnated with silica gel (2x20 cm) used in the standard method will not be commercially ...
Laura A, Eggert, Michael D, Dick, Douglas W, Mahoney, Joseph P, Olson, Gregory L, Werner, Joseph C, Hung   +5 more
openaire   +2 more sources

Miniaturized radiochemical purity testing for99mTc-HMPAO,99mTc-HMDP, and99mTc-tetrofosmin

, 2017
Quick methods are functional in clinical practice to ensure the fastest availability of radiopharmaceuticals. For this purpose, we investigated the radiochemical purity of the widely used99mTc-hydroxymethylene diphosphonate,99mTc-hexamethylpropyleneamine
Paola A. Erba, Erba, Paola A., Roberta Zanca, Angela G. Cataldi, Lazzeri, Elena, Boni, Roberto, Roberto Boni, Martina Sollini, Ana de la Fuente, de la FUENTE JOANIQUET, ANA, Cataldi, Angela G., Elena Lazzeri, Zanca, Roberta, Sollini, Martina, Giuliano Mariani, Mariani, Giuliano   +15 more
core   +1 more source

Determination of Radiochemical Purity of 99mTc-DTPA Using One-System Method of Paper Chromatography [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The more efficient and effective quality control techniques for 99mTc-DTPA are needed because 99mTc has a short half-life of around 6.0 hours. We have succeeded in developing a one-system of TLC for radiochemical purity testing system that is faster and ...
Maskur Maskur, Enny Lestari, Amal Rezka Putra, Dede Kurniasih, Endang Sarmini, Yayan Tahyan, Adang Hardi Gunawan, Arni Aries   +7 more
doaj  

Automated synthesis and quality control of [68Ga]Ga-PentixaFor using the Gaia/Luna Elysia-Raytest module for CXCR4 PET imaging

EJNMMI Radiopharmacy and Chemistry, 2023
Background [68Ga]Ga-PentixaFor is a promising radiotracer for positron emission tomography imaging of several human tumors overexpressing the chemokine receptor-4 (CXCR4).
Thomas Daniel, Clara Balouzet Ravinet, Jérôme Clerc, Rui Batista, Yvan Mouraeff   +4 more
doaj   +1 more source

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Development of an HPLC method for the radiochemical purity evaluation of [18F]fluoroestradiol

Brazilian Journal of Radiation Sciences, 2019
18F-Fluoroestradiol ([18F]FES), an estrogen analog, is a radiopharmaceutical used in Positron Emission Tomography (PET) that allows evaluating the tumor cell receptor profile and the best therapy strategy, the staging, the prognosis and the response to ...
Ana Carolina de Araujo Bispo, Leonardo Tafas Constantino Nascimento, Flávia Mesquita Costa, Juliana Batista da Silva, Marcelo Mamede   +4 more
doaj   +1 more source

An Alternative Method for Determining the Radiochemical Purity of 99mTc-Tetrofosmin [PDF]

Journal of Nuclear Medicine Technology, 2011
The instant thin-layer chromatographic method of determining the radiochemical purity of (99m)Tc-tetrofosmin recommended by the manufacturer uses a mixture of acetone and dichloromethane (35:65 v/v) as the solvent and a silica gel (SG) strip as the solid phase. Currently, SG strips are not available commercially and an alternative solid phase is needed.
Kanak C, Amin, Sagar, Patel, Aniruddha, Doke, Gopal B, Saha   +3 more
openaire   +2 more sources

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source