Results 21 to 30 of about 186,978 (199)

Preparation of 99mTc-quercetion as a labeled flavonoid and the study of its biological distribution in mice with skin tumor [PDF]

مجله علوم و فنون هسته‌ای, 2021
The aim of this study was to label quercetin as a natural flavonoid compound with technetium-99m and to study its biological distribution in different tissues of C57 mice bearing melanoma B16F10 cells for tumor diagnosis. Quercetin labeling was performed
M. Ghalbi Ahangari, M. Moridi Farimani, M. Erfani, M. Goudarzi   +3 more
doaj   +1 more source

Improved quality control of [177Lu]Lu-PSMA I&T

EJNMMI Radiopharmacy and Chemistry, 2023
Background Targeted radionuclide therapy with [177Lu]Lu-PSMA I&T (zadavotide guraxetan) has proven high efficacy and safety in treating patients with advanced prostate cancer worldwide.
Martin Kraihammer, Piotr Garnuszek, Andreas Bauman, Michael Maurin, Manuel Alejandre Lafont, Roland Haubner, Elisabeth von Guggenberg, Michael Gabriel, Clemens Decristoforo   +8 more
doaj   +1 more source

One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

EJNMMI Radiopharmacy and Chemistry, 2021
Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors ...
Sadahiro Naka, Tadashi Watabe, Thomas Lindner, Jens Cardinale, Kenta Kurimoto, Melissa Moore, Mitsuaki Tatsumi, Yuriko Mori, Eku Shimosegawa, Frank Valla, Hiroki Kato, Frederik L. Giesel   +11 more
doaj   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

Angewandte Chemie, EarlyView.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy, Yoon Ho Lee, Ali Salehi Farid, Heydar Moravej, Sina Djafari Rouhani, Jennifer E. Rowley, Mohammad Rashidian, Mark D. Distefano   +7 more
wiley   +2 more sources

The Semi-automatic Synthesis of 18F-fluoroethyl-choline by Domestic FDG Synthesizer

Journal of Isotopes, 2016
As an important complementary imaging agent for 18F-FDG, 18F-fluoroethyl-choline (18F-FECH) has been demonstrated to be promising in brain and prostate cancer imaging.
ZHOU Ming, ZHANG Xiao-jun, LIU Jian, LI Yun-gang   +3 more
doaj   +1 more source

Study on identification method of ¹⁴C-metsulfuron-methyl

浙江大学学报. 农业与生命科学版, 2001
The chemical purity of 14C-metsulfuron-methyl was determined by high performance liquid chromatography (HPLC), its radiochemical purity was measured by HPLC-LSC (Liquid Scintillation Counter) and TLC-isotope imaging analysis (TLC-IIA), respectively.
YE Qing-fu, SUN Jin-he
doaj   +1 more source

An Alternative Method for Determining the Radiochemical Purity of 99mTc-Tetrofosmin [PDF]

Journal of Nuclear Medicine Technology, 2011
The instant thin-layer chromatographic method of determining the radiochemical purity of (99m)Tc-tetrofosmin recommended by the manufacturer uses a mixture of acetone and dichloromethane (35:65 v/v) as the solvent and a silica gel (SG) strip as the solid phase. Currently, SG strips are not available commercially and an alternative solid phase is needed.
Kanak C, Amin, Sagar, Patel, Aniruddha, Doke, Gopal B, Saha   +3 more
openaire   +2 more sources

Miniaturized radiochemical purity testing for99mTc-HMPAO,99mTc-HMDP, and99mTc-tetrofosmin

, 2017
Quick methods are functional in clinical practice to ensure the fastest availability of radiopharmaceuticals. For this purpose, we investigated the radiochemical purity of the widely used99mTc-hydroxymethylene diphosphonate,99mTc-hexamethylpropyleneamine
Paola A. Erba, Erba, Paola A., Roberta Zanca, Angela G. Cataldi, Lazzeri, Elena, Boni, Roberto, Roberto Boni, Martina Sollini, Ana de la Fuente, de la FUENTE JOANIQUET, ANA, Cataldi, Angela G., Elena Lazzeri, Zanca, Roberta, Sollini, Martina, Giuliano Mariani, Mariani, Giuliano   +15 more
core   +1 more source

Determination of Radiochemical Purity of 99mTc-DTPA Using One-System Method of Paper Chromatography [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The more efficient and effective quality control techniques for 99mTc-DTPA are needed because 99mTc has a short half-life of around 6.0 hours. We have succeeded in developing a one-system of TLC for radiochemical purity testing system that is faster and ...
Maskur Maskur, Enny Lestari, Amal Rezka Putra, Dede Kurniasih, Endang Sarmini, Yayan Tahyan, Adang Hardi Gunawan, Arni Aries   +7 more
doaj  

Automated synthesis and quality control of [68Ga]Ga-PentixaFor using the Gaia/Luna Elysia-Raytest module for CXCR4 PET imaging

EJNMMI Radiopharmacy and Chemistry, 2023
Background [68Ga]Ga-PentixaFor is a promising radiotracer for positron emission tomography imaging of several human tumors overexpressing the chemokine receptor-4 (CXCR4).
Thomas Daniel, Clara Balouzet Ravinet, Jérôme Clerc, Rui Batista, Yvan Mouraeff   +4 more
doaj   +1 more source