General Methods, Application Development and Related Problems of Radiochemical Purity Analysis
Journal of Isotopes, 2023 In recent years, the development of innovative radiopharmaceuticals has become a “hot spot”. In these development processes, it is crucial for researchers to createa radiochemical purity analysis method which is accurate, fast, and convenient.
YAO Jingjing;YANG Weifang;FAN Mingxuan;LU Jie
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A Modified Method for Increasing Radiochemical Purity of I-125 for Radiopharmaceuticals
Atom Indonesia, 2023 Iodine-125 (125I) is one of the radioisotopes widely used in radiopharmaceuticals for diagnosis and therapy of various cancers. Recent reports indicate that there has been shortages in the world supply of this radioiodine isotope.
M Maiyesni +6 more
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Indonesian Journal of Chemistry, 2018 Radiotherapy is one of healing method of cancer using radionuclide elements. The radionuclide scandium-46 (46Sc) has a half-life of 83.8 days, beta emission 0.35 MeV and gamma emission 899 and 1120 keV is suitable for studying the chemical aspects ...
Duyeh Setiawan +2 more
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Evaluation of radiochemical purities of some radiopharmaceuticals in Shiraz Namazi teaching hospital [PDF]
Trends in Pharmaceutical Sciences, 2015 Radiopharmaceuticals are a special group of drugs since many of them are eventually prepared in the hospital and the nuclear medicine department is therfore responsible for meeting quality criteria such as sterility, radionuclide, radiochemical and ...
Hossein Sadeghpour +4 more
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Establishment of Ion Chromatography Method for Identification and Determination of the Radiochemical Purity of [11C]Choline Injection [PDF]
Journal of Isotopes[11C]choline is a normal tracer using for PET/CT，identification of [11C]choline and analysis its radiochemical purity are important to guarantee the validity and safety of tracer.
Guojin ZHANG, Shanzhen HE
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Automated radiosynthesis of 2-[18F]BPA for PET-based planning of boron neutron capture therapy (BNCT): rational precursor design, radiofluorination, and characterization of methodology [PDF]
EJNMMI Radiopharmacy and ChemistryBackground Boron neutron capture therapy relies on the selective accumulation of boron-containing compounds in tumor tissue, making accurate quantification of boron distribution essential for effective treatment planning.
Vincenzo Paolillo +4 more
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Radiolabeled Angiopep-2 Peptide Vector as a Preclinical Platform for Blood-Brain Barrier Targeting: Synthesis, Radiolabeling, and Preliminary In Vivo Biodistribution in Mice. [PDF]
J Pept SciThe developed DOTA‐Angiopep‐2 conjugate was well tolerated in glioma cells and enabled high‐yield radiolabeling with 177Lu and 161Tb. The 161Tb conjugate showed brain delivery with predominantly renal clearance, supporting a stable radiotheranostic platform for BBB‐targeted glioma therapy and SPECT imaging.
Fotou E +10 more
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Anales (Asociación Física Argentina), 2021 This work analyzes the reliability of the radiochemical purity control method of 99mTc-MIBI used in nuclear medicine services and the influence of the greater presence of radiochemical impurities in the diagnostic quality of the obtained images.
N. Guisande +9 more
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Radiolabeling Technique of Silver Nanoparticles (AgNPs) with Iodine-131 Radionuclide
Atom Indonesia, 2020 Radiotherapy is an effective cancer therapy, where a certain dose of radiation is aimed specifically at target and is unaffecting to normal tissue. A selectiveradionuclide must be attached to the specific targeted organ.
U.N. Sholikhah +5 more
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The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method [PDF]
Journal of Pure and Applied Chemistry Research, 2021 Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown.
Amal Rezka Putra +6 more
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