General Methods, Application Development and Related Problems of Radiochemical Purity Analysis
In recent years, the development of innovative radiopharmaceuticals has become a “hot spot”. In these development processes, it is crucial for researchers to createa radiochemical purity analysis method which is accurate, fast, and convenient.
YAO Jingjing;YANG Weifang;FAN Mingxuan;LU Jie
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A Modified Method for Increasing Radiochemical Purity of I-125 for Radiopharmaceuticals [PDF]
Iodine-125 (125I) is one of the radioisotopes widely used in radiopharmaceuticals for diagnosis and therapy of various cancers. Recent reports indicate that there has been shortages in the world supply of this radioiodine isotope.
M Maiyesni +6 more
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Radiotherapy is one of healing method of cancer using radionuclide elements. The radionuclide scandium-46 (46Sc) has a half-life of 83.8 days, beta emission 0.35 MeV and gamma emission 899 and 1120 keV is suitable for studying the chemical aspects ...
Duyeh Setiawan +2 more
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Establishment of Ion Chromatography Method for Identification and Determination of the Radiochemical Purity of [11C]Choline Injection [PDF]
[11C]choline is a normal tracer using for PET/CT,identification of [11C]choline and analysis its radiochemical purity are important to guarantee the validity and safety of tracer.
Guojin ZHANG, Shanzhen HE
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This work analyzes the reliability of the radiochemical purity control method of 99mTc-MIBI used in nuclear medicine services and the influence of the greater presence of radiochemical impurities in the diagnostic quality of the obtained images.
N. Guisande +9 more
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Radiolabeling Technique of Silver Nanoparticles (AgNPs) with Iodine-131 Radionuclide
Radiotherapy is an effective cancer therapy, where a certain dose of radiation is aimed specifically at target and is unaffecting to normal tissue. A selectiveradionuclide must be attached to the specific targeted organ.
U.N. Sholikhah +5 more
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A comparative assessment of radiochemical purity and yield of [<sup>18</sup>F]PSMA-1007 production using two different automated synthesis platforms: a head-to-head comparison. [PDF]
Background Glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA) is overexpressed in 90–100% of prostate cancer cells. The radiopharmaceutical [18F]PSMA-1007, recognised as a PET tracer for prostate cancer imaging,
Cossandi M +11 more
europepmc +2 more sources
The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method [PDF]
Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown.
Amal Rezka Putra +6 more
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Evaluation of radiochemical purities of some radiopharmaceuticals in Shiraz Namazi teaching hospital [PDF]
Radiopharmaceuticals are a special group of drugs since many of them are eventually prepared in the hospital and the nuclear medicine department is therfore responsible for meeting quality criteria such as sterility, radionuclide, radiochemical and ...
Hossein Sadeghpour +4 more
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Iodine-131 labeled genistein as a potential radiotracer for breast cancer
Objective: Genistein is an isoflavone compound that has been proven to have anticancer activity and is capable of binding to estrogen β receptors with Selective Estrogen Receptor Modulators (SERMs) properties, and has a strong affinity to inhibit the ...
Danni Ramdhani +4 more
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