Results 41 to 50 of about 24,433 (235)

Chemistry course for radiochemistry engineers on the platform Moodle: a support to self-education for undergraduate students [PDF]

, 2011
The education challenges at present times include the incorporation of information and communication technologies (ICT) in the learning-teaching process.
Jáuregui Haza, Ulises Javier, Lau Gonzalez, Maritza, Le Bolay, Nadine   +2 more
core  

Microfluidics: A Groundbreaking Technology for PET Tracer Production?

Molecules, 2013
Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has attracted increasing interest within the last decade. The technical advantages of microfluidics, in particular the high surface to volume ratio and resulting fast ...
Björn Wängler, Carmen Wängler, Stefan Riese, Peter Bartenstein, Simon Lindner, Ruben Salvamoser, Victor Samper, Christian Rensch, Alexander Jackson   +8 more
doaj   +1 more source

Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) ¹⁸F-Radiopharmaceuticals

Pharmaceuticals, 2021
The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules, such as peptides, proteins and biologically relevant small molecules, has improved the generation of 18F-radiopharmaceuticals for medical imaging.
Lexi Gower-Fry, Travis Kronemann, Andreas Dorian, Yinglan Pu, Carolin Jaworski, Carmen Wängler, Peter Bartenstein, Leonie Beyer, Simon Lindner, Klaus Jurkschat, Björn Wängler, Justin J. Bailey, Ralf Schirrmacher   +12 more
doaj   +1 more source

Fate of Some Common Radionuclides Found in Dardanelle Lake [PDF]

, 1979
Four factors influence the concentrations of radionuclides in Dardanelle Lake water: injections due to fallout and discharge from Nuclear I coupled with losses due to decay, to dilution and to sedimentation.
Chittenden, David M., II
core   +2 more sources

Expanding the Chemistry Palette for Radiotracer Synthesis

CHIMIA, 2020
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic methods ...
Jennifer Lamb, Faustine d'Orchymont, Rachael Fay, Florian Gribi, Jose Esteban Flores, Melanie Gut, Simon Klingler, Patricia Pires, Jan Bühler, Shamisa Behmaneshfar, Amaury Guillou, Daniel F. Earley, Jason P. Holland   +12 more
doaj   +1 more source

Application of Palladium-Mediated 18F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation [PDF]

, 2013
New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated.
Carlin, Stephen M., Hooker, Jacob M, Kamlet, Adam, Lee, Eunsung, Moseley, Christian K., Neumann, Constanze Nicole, Ritter, Tobias, Stephenson, Nickeisha A   +7 more
core   +3 more sources

Radium Speciation in Simulated Digestive Biofluids: Insights from Electrospray Ionization Mass Spectrometry and Thermodynamic Modeling

Analysis &Sensing, EarlyView.
Electrospray ionization mass spectrometry (ESI‐MS) combined with thermodynamic modeling provides the first direct characterization of radium speciation in synthetic gastrointestinal biofluids. Free Ra2+ ions predominate with minimal protein binding and negligible EDTA complexation. Crown ethers enable effective Ra complexation.
Linus Holtmann, Tim Schmalz, Tobias Weissenborn, Felix Stäger, Beate Riebe, Clemens Walther   +5 more
wiley   +1 more source

Molecular Imaging with 68Ga Radio-Nanomaterials: Shedding Light on Nanoparticles

Applied Sciences, 2018
The combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the
Irene Fernández-Barahona, María Muñoz-Hernando, Juan Pellico, Jesús Ruiz-Cabello, Fernando Herranz   +4 more
doaj   +1 more source

Effective Preparation of [¹⁸F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor

Molecules, 2022
(1) Background: [18F]Flumazenil 1 ([18F]FMZ) is an established positron emission tomography (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABAA in the brain.
Mohammad B. Haskali, Peter D. Roselt, Terence J. O’Brien, Craig A. Hutton, Idrish Ali, Lucy Vivash, Bianca Jupp   +6 more
doaj   +1 more source

Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B) [PDF]

, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Nag, Sangram
core   +2 more sources