Results 41 to 50 of about 27,411 (234)
EJNMMI Radiopharmacy and Chemistry, 2021 The aluminium-[ 18 F]fluoride ([ 18 F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharmaceutical ...
S. Archibald, L. Allott
semanticscholar +1 more source
Novel Receptor Tyrosine Kinase Pathway Inhibitors for Targeted Radionuclide Therapy of Glioblastoma
Pharmaceuticals, 2021 Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently leads to the activation of many ...
Julie Bolcaen +5 more
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Scientific Reports, 2017 In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access to ...
Andrew V. Mossine +5 more
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The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute
CHIMIA, 2020 Radionuclide production and development has a long history at the Paul Scherrer Institute (PSI) and dates back to the founding times of its forerunner institutions: the Federal Institute for Reactor Research and the Swiss Institute for Nuclear Research ...
Pascal V. Grundler +5 more
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Pharmaceutics, 2021 Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to αvβ3 integrin.
Barbara Gyuricza +6 more
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Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions
Pharmaceuticals, 2023 Fibrosis accompanies various pathologies, and there is thus an unmet medical need for non-invasive, sensitive, and quantitative methods for the assessment of fibrotic processes.
Olof Eriksson, Irina Velikyan
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Targeted Alpha Therapy: Progress in Radionuclide Production, Radiochemistry, and Applications
Pharmaceutics, 2020 This review outlines the accomplishments and potential developments of targeted alpha (α) particle therapy (TAT). It discusses the therapeutic advantages of the short and highly ionizing path of α-particle emissions; the ability of TAT to complement and ...
Bryce J B Nelson, J. Andersson, F. Wuest
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Radiochemistry and nuclear chemistry workforce in the United States
Journal of Applied Clinical Medical Physics, 2022 The disciplines of radiochemistry and nuclear chemistry have direct applications in the fields of national security, nuclear medicine, nuclear power production, and environmental management.
S. Y. Tolmachev +5 more
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The Rise of Synaptic Density PET Imaging
Molecules, 2020 Many neurological disorders are related to synaptic loss or pathologies. Before the boom of positrons emission tomography (PET) imaging of synapses, synaptic quantification could only be achieved in vitro on brain samples after autopsy or surgical ...
Guillaume Becker +3 more
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Innovative Peptide Bioconjugation Chemistry with Radionuclides: Beyond Classical Click Chemistry. [PDF]
Pharmaceuticals (Basel)Background: The incorporation of radionuclides into peptides and larger biomolecules requires efficient and sometimes biorthogonal reaction conditions, to which click chemistry provides a convenient approach.
Leier S, Wuest F.
europepmc +2 more sources