Results 101 to 110 of about 12,311,283 (257)

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Radiological Physics simulation of radiographic image acquisition.

, 2020
Radiological Physics simulation of radiographic image ...
Peter Riley (13089801)
core  

Nonlinear retinal image enhancement for vessel detection

, 2017
Retinal vessel detection is an essential part of the computer-aided diagnosis of eye diseases. Due to non-perfect imaging environment, retinal images often appear with intensity variations and artificial noises.
Jiang, Xudong, Wang, Xiaohong, Xiaohong Wang, Xudong Jiang   +3 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Accuracy of digital image processing in radiographic early caries detection

Majalah Kedokteran Gigi Indonesia
Tooth surface with early caries lesion can remineralize into sound tooth surface with early intervention. However, early caries lesion is difficult to detect and frequently goes unnoticed during clinical or radiographic examinations.
Menik Priaminiarti, Giovanni Atmadja, Inka Saraswati, Hanna Huzaima Bachtiar Iskandar   +3 more
doaj   +1 more source

Digital radiographic image enhancement for weld defect detection using smoothing and morphological transformations

, 2012
Accurate inspection of welded materials is important in relation to achieve acceptable standards. Radiography, a non-destructive test method, is commonly used to evaluate the internal condition of a material with respect to defect detection. The presence
Husna Zayadi
core  

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou, Mingke Zhao, Zhiwei Ling, Lianqi Peng, Bide Tong, Huaizhen Liang, Hongchuan Wang, Di Wu, Yifan Du, Zhi Du, Shihao Zhang, Yuyuan Jia, Yifan Qian, Gan Xu, Liuliang He, Gang Li, Shun Zhang, Lei Tan, Kun Wang, Xiaobo Feng, Cao Yang, Zhiwei Liao   +21 more
wiley   +1 more source

Improving the Quality of X-Ray Images of the Lungs of COVID-19 and Healthy Patients Using the Contrast Limited Adaptive Histogram Equalization (CLAHE) Method in Batam

Journal of Electrical Engineering and Computer Sciences
X-ray imaging is a widely used technique for observing lung patients conditions. Compared to other radiographic methods, X-ray is more accessible, cost-effective, and commonly available in healthcare facilities. However, digital X-ray images often suffer
Marisha Pertiwi, Fortia Magfira, Dwi Rahmaisyah, M. Hasbi Sidqi Alajuri   +3 more
doaj   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

Dual-Filter X-Ray Image Enhancement Using Cream and Bosso Algorithms: Contrast and Entropy Optimization Across Anatomical Regions

Journal of Imaging
This study introduces a dual-filter X-ray image enhancement technique designed to elevate the quality of radiographic images of the knee, breast, and wrist, employing the Cream and Bosso algorithms.
Antonio Rienzo, Miguel Bustamante, Ricardo Staub, Gastón Lefranc   +3 more
doaj   +1 more source