Results 41 to 50 of about 129,731 (303)

Diagnostic efficacy of chemiluminescence immunoassay versus radioimmunoassay in screening primary aldosteronism

open access: yesDi-san junyi daxue xuebao, 2019
Objective To compare the sensitivity and specificity of chemiluminescence immunoassay (CLIA) and radioimmunoassay (RIA) in detection of aldosterone and renin, and to explore the optional detection methods and indicators for screening primary ...
HONG Yangning   +3 more
doaj   +1 more source

Adrenocortical Adenocarcinoma in a Syrian Golden Hamster (Mesocricetus auratus) With Suspected Hyperadrenocorticism. [PDF]

open access: yesVet Med Sci
A 2‐year‐old female golden hamster presented with non‐pruritic alopecia of the hindquarters. Diagnostic imaging and cytological evaluation revealed a unilateral adrenal mass consistent with an adrenocortical tumour, while biochemical analyses suggested corticosteroid secretion.
Billaux MF   +6 more
europepmc   +2 more sources

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

open access: yesAdvanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza   +9 more
wiley   +1 more source

PREGNANCY-ASSOCIATED GLYCOPROTEIN CONCENTRATIONS IN NON-PREGNANT COWS: A CASE STUDY

open access: yesRUDN Journal of Agronomy and Animal Industries, 2018
The aim of the present work was undertaken to describe three cases of the bPAG concentration measure by three RIA systems during the post-partum period in non-pregnantcow.
Abdelhanine Ayad, Kamal Touati
doaj   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Assessing cortisol concentration in different matrices: predictive potential and relationship with production levels, lactation stage and parity in dairy buffaloes

open access: yesItalian Journal of Animal Science
Cortisol is the primary biomarker associated with the hypothalamic–pituitary–adrenal (HPA) axis. This research aimed at assessing the predictive potential and the relationship of cortisol concentrations in four media (blood, milk, whey and hair) with ...
Alessio Cotticelli   +7 more
doaj   +1 more source

Benefits of Macitentan in Patients with Pulmonary Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesGlobal Heart, 2023
Background: This systematic review and meta-analysis aimed to determine the efficacy of macitentan in patients with pulmonary hypertension (PH). Methods: A systematic search was made of PubMed, Embase, Cochrane Library, and clinicaltrials.gov, without ...
Jinlv Qin, Guizuo Wang, Dong Han
doaj   +1 more source

An ultra‐processed food‐based cafeteria diet induces obesity, metabolic dysfunction, and tissue‐specific gene dysregulation in C57BL/6 mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte   +9 more
wiley   +1 more source

Terminal deoxynucleotidyltransferase. Serological studies and radioimmunoassay [PDF]

open access: yes, 1976
Mouse antisera against calf terminal deoxynucleotidyltransferase (terminal transferase) have been prepared. The sera have been used to characterize terminal transferase both by studying inhibition of enzyme activity and by developing a competition ...
Baltimore, David   +2 more
core  

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

open access: yesAdvanced NanoBiomed Research, EarlyView.
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang   +8 more
wiley   +1 more source

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