Results 41 to 50 of about 121 (118)

Narcolepsy and rapid eye movement sleep

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini   +4 more
wiley   +1 more source

Overnight Dynamics of Ventricular Cerebrospinal Fluid Amyloid‐Beta, Lactate and Hypocretin in Patients With Hydrocephalus: A Pilot Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT This pilot observational study evaluated whether frequent overnight sampling of ventricular cerebrospinal fluid could clarify how sleep, hypocretin and lactate relate to amyloid‐β42 dynamics in adults with hydrocephalus. Seven participants underwent hourly ventricular cerebrospinal fluid sampling from early evening to late morning during ...
Casper Schwartz Riedel   +4 more
wiley   +1 more source

COVID‐19–Induced Narcolepsy Type I With Cataplexy: A Short Report

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type I is a rare neurological sleep disorder characterised by chronic excessive daytime sleepiness, cataplexy, and low orexin (hypocretin) levels. Infection with SARS‐CoV‐2 has been linked to neurological and neuropsychiatric sequelae, but cases of post‐COVID narcolepsy remain extremely uncommon.
Torsten Vinding Merinder   +2 more
wiley   +1 more source

Improved Glucagon Sensitivity Following Weight Loss: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis investigated the effect of weight loss in people with obesity on two biomarkers of glucagon resistance: fasting plasma glucagon and alanine. Methods A comprehensive search was conducted in Medline and Embase. Random‐effects meta‐analyses and correlation analyses were performed.
Hye‐Rin Charlotte Kim   +4 more
wiley   +1 more source

Drought‐Induced Abscisic Acid Accumulation in Soybean Roots Depends on NCED Gene Expression More Than Shoot‐to‐Root ABA Transport

open access: yesPlant, Cell &Environment, Volume 49, Issue 7, Page 4166-4177, July 2026.
Abstract Abscisic acid (ABA) is a key phytohormone in plant responses to water deficit. Although there is extensive evidence that roots can synthesise ABA, recent findings suggest that local synthesis in response to dehydration contributes little to the root ABA pool compared to shoot‐sourced ABA.
Jaime Puértolas   +4 more
wiley   +1 more source

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

The Effect of Lipemia on Insulin and Adiponectin Measurement in Equine Blood Samples

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Lipemia is a common comorbidity in horses with obesity or equine metabolic syndrome, but the impact of lipemia on the measurement of insulin and adiponectin has not been evaluated. Objective To evaluate endogenous and exogenous lipemic interference with equine insulin and adiponectin measurements via several commercial assays ...
Kimberly L. Hallowell   +3 more
wiley   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss   +11 more
wiley   +1 more source

The Silver Jubilee (2025) of Insulin Glargine: Introducing the Era of Long‐Acting Insulin Analogues for Diabetes Mellitus

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5527-5541, July 2026.
ABSTRACT In the year 2000 the first once daily long‐acting bioengineered insulin analogue (LAIA), insulin glargine (‘glargine’), a true basal insulin (BI), became available for clinical use. This led to the decline in the 50‐year‐old era and prominence of the intermediate‐acting insulins, neutral protamine Hagedorn (NPH) and lente, requiring twice ...
Geremia B. Bolli   +9 more
wiley   +1 more source

Postprandial Glucagon Action in the Human Brain

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5926-5938, July 2026.
ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner   +11 more
wiley   +1 more source

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