Results 21 to 30 of about 121 (118)

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner   +10 more
wiley   +1 more source

Effects of Summer Heat Stress on Physiological Parameters and Reproductive Efficiency of Barbarine Ewes Under Natural Outdoor or Indoor Conditions

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Climate change and rising ambient temperatures increasingly challenge sheep production systems in arid and semi‐arid regions, particularly during the summer breeding season. This study evaluated the effects of heat stress and direct solar exposure on physiological responses, metabolic profile, and reproductive performance of Barbarine ewes, a ...
Samia Khnissi   +4 more
wiley   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Evaluation of a non‐radioactive rapid test for determination of serum progesterone in South American camelids

open access: yesVeterinary Record, EarlyView.
Abstract Background Determination of the serum progesterone (P4) concentration is of high importance in reproductive medicine and may be applied for diagnosing pregnancy in South American camelids. P4 measurements in alpacas and llamas are usually performed using immunoassays, which are time consuming and require appropriate expertise of laboratory ...
Lina Längerer   +5 more
wiley   +1 more source

Quantification of steroid hormones in free‐ranging Apennine wolf Canis lupus italicus hair samples collected post‐mortem

open access: yesWildlife Biology, EarlyView.
After decades of dramatic reductions in their populations, Italian wolves have begun recolonizing parts of their historic range. This growth in populations can lead to potential conflicts with human activities, which remain the main cause of wolf mortality.
Ilaria Troisio   +8 more
wiley   +1 more source

First Non‐Invasive Monitoring of Fecal Steroids in Greater Caribbean Manatees (Trichechus manatus manatus)

open access: yesZoo Biology, EarlyView.
This study established the first fecal hormonal reference values (P4/E2) for the Greater Caribbean manatee. Using non‐invasive ELISA, the authors found no significant differences between mature and immature females, highlighting that long‐term monitoring and ultrasounds are essential to fully understand their complex reproductive cycles.
Vanessa Bermúdez‐Cardona   +3 more
wiley   +1 more source

Rapid hormonal rise in honey bees due to heat‐shock is mitigated by a primer pheromone

open access: yesInsect Science, EarlyView.
We show that honey bee foragers increased juvenile hormone (JH) titers significantly after heat‐shocked for 1 h at 40 °C, but this increase is dependent on social conditions. Increase of JH titers only happened when bees were isolated (one worker bee per vial) but not in groups.
Thomas Rachman, Zachary Y. Huang
wiley   +1 more source

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

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