Results 71 to 80 of about 123,812 (299)

Traumatic stress‐enhanced ethanol drinking: Sex, but not stress responsivity, alters sensitivity to the effects of a CRF‐R1 antagonist and a GPR39 agonist in mice

Alcohol, Clinical and Experimental Research, EarlyView.
Here we showed that a corticotropin releasing factor receptor 1 antagonist (NBI‐27914) and a G‐protein coupled receptor 39 agonist TC‐G 1008 significantly suppressed binge drinking in male and female mice. However, their ability to decrease predator stress (PS)‐enhanced drinking did not differ between “PS‐sensitive” versus “PS‐resilient” subgroups ...
Melinda L. Helms, Deborah A. Finn, Michelle A. Nipper, Andrey E. Ryabinin, Rita P. Cervera‐Juanes   +4 more
wiley   +1 more source

Faecal steroid measurements for the assessment of reproductive function in Japanese quail (Coturnix coturnix japonica) and kakapo (Strigops habroptilus) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University [PDF]

, 2002
The kakapo (Strigops habroptilus) is an endangered parrot endemic to New Zealand and little is known of its reproductive physiology. Reproductive function is conventionally determined by the measurement of reproductive steroids in plasma samples. This is
Hawke, Emma Jane
core  

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? EPISODE I: CRIME

Andrology, EarlyView.
Abstract This is the first episode of a series of four discussions on the differences between males and females, in apparently non‐andrological fields. You will read the transcript of discussions that actually took place at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogues of ancient Greece.
Giulia Brigante, Giulia D'Angelo, Vanessa Caccin, Silvia Coluccia, Immacolata Conte, Veronica Maria Demichelis, Rossana Cecchi, Manuela Simoni   +7 more
wiley   +1 more source

Determination of fluphenazine, related phenothiazine drugs and metabolites by combined high-performance liquid chromatography and radioimmunoassay. [PDF]

, 1981
Antibodies have been produced in rabbits immunized with a fluphenazine succinate-human serum albumin conjugate. By radioimmunoassay it is possible to quantify fluphenazine (FPZ), related phenothiazine drugs and several of their metabolites at the ...
Goldstein, SA, Van Vunakis, H
core  

Lithium treatment reduces the renal kallikrein excretion rate [PDF]

, 1990
Lithium treatment reduces the renal kallikrein excretion rate. Lithium salts are widely used agents for the prophylactic treatment of affective disorders. Lithium salts may be associated with distal nephron dysfunction.
Albrecht, American Psychiatric Association, Amundsen, Angst, Aurell, Baastrup, Barajas, Battle, Bendz, Birch, Bönner, Bönner, Bönner, Caroline Reinhard, Christensen, Colt, Edwin Fink, Fejes-Toth, Gross, Gross, Haber, Hansen, Heinrich Sauer, Hestbech, Horwitz, Jacobsen, Kling, Mann, Marcos Marin-Grez, Marin-Grez, Martinez-Maldonado, McAuliffe, Miller, Mitas, Murphy, Noda, Norgaard, Nustad, O'Connor, Peter Gross, Proud, Rascher, Scicli, Singer, Singer, Sustarsic, Vecsei, Vio, Walker, Walker   +49 more
core   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Toxicological analyses of the bone matrix: Successes and challenges

Archaeometry, EarlyView.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano, Lucie Biehler‐Gomez, Cristina Cattaneo, Domenico Di Candia   +3 more
wiley   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate, Patricia Miranda‐Azpiazu, Igor Horrillo, Rebeca Diez‐Alarcia, J. Javier Meana   +4 more
wiley   +1 more source

Development of an immunoprecipitation assay for detecting anti‐3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase autoantibodies using a non‐radioactive biotinylated recombinant protein

Clinical and Experimental Neuroimmunology, EarlyView.
Principle and performance of an immunoprecipitation assay for detecting anti‐3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR) autoantibodies using a non‐radioactive biotinylated recombinant protein. This new assay can serve as a potential alternative to the gold standard immunoprecipitation assay for detecting anti‐anti‐3‐hydroxy‐3 ...
Yukihiro Nishikawa, Kimiko Hasegawa, Hiroki Abe, Shun Matsuzawa, Takuya Isayama, Ran Nakashima, Yoshihiko Saito, Ichizo Nishino, Masataka Kuwana   +8 more
wiley   +1 more source

Developments in albuminuria testing: A key biomarker for detection, prognosis and surveillance of kidney and cardiovascular disease—A practical update for clinicians

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Albuminuria, the abnormal presence of albumin in urine, is a key marker of kidney damage and a strong predictor of kidney and cardiovascular outcomes. Its clinical significance has evolved from early historical observations to its current role in chronic kidney disease (CKD) detection, risk stratification and treatment monitoring.
Jelle M. Beernink, Dominique van Mil, Gozewijn D. Laverman, Hiddo J. L. Heerspink, Ron T. Gansevoort   +4 more
wiley   +1 more source