Results 181 to 190 of about 13,452 (195)

A Self‐Enhancing Nanoreactor Reinforces Radioimmunotherapy by Reprogramming Nutrients and Redox Metabolisms

Advanced Functional Materials, 2023
Altered metabolism of cancer cells reshapes the unique tumor microenvironment (TME) with glucose addiction and high antioxidant levels, resulting in a strong alliance to promote tumor progression and treatment failure.
Mengfei Hou, Haiyang Su, Qinghe Wu, Wenshe Sun, Pengli Zhang, Yifei Jiang, Kun Qian, Chunfu Zhang   +7 more
semanticscholar   +1 more source

Personalized Carbon Monoxide‐Loaded Biomimetic Single‐Atom Nanozyme for Ferroptosis‐Enhanced FLASH Radioimmunotherapy

Advanced Functional Materials, 2023
Ultra‐high dose rate radiotherapy (FLASH‐RT) has emerged as a novel tool for cancer radiotherapy owing to its extremely rapid radiation delivery to target species.
Meng Lyu, Min Luo, Jingyun Li, O. Akakuru, Xiaowan Fan, Zhen Cao, Kelong Fan, Wei Jiang   +7 more
semanticscholar   +1 more source

Nanozyme‐Coated Bacteria Hitchhike on CD11b+ Immune Cells to Boost Tumor Radioimmunotherapy

Advances in Materials, 2023
Bacterial‐based delivery strategies have recently emerged as a unique research direction in the field of drug delivery. However, bacterial vectors are quickly phagocytosed by immune cells after entering the bloodstream.
Hanghang Li, Pei Pei, Qing He, Xuexue Dong, Chonghai Zhang, Wenhao Shen, Hua Chen, Lin Hu, Yugui Tao, Kai Yang   +9 more
semanticscholar   +1 more source

EISA in Tandem with ICD to Form In Situ Nanofiber Vaccine for Enhanced Tumor Radioimmunotherapy

Advanced Healthcare Materials, 2023
Radiotherapy (RT) can produce a vaccine effect and remodel a tumor microenvironment (TME) by inducing immunogenic cell death (ICD) and inflammation in tumors.
Hongjing Luo, Hongmei Cao, Haixue Jia, Y. Shang, Jinjian Liu, Han Gui, Cuihong Yang, Chunhua Ren, Zhongyan Wang, Jianfeng Liu   +9 more
semanticscholar   +1 more source

Zoledronic Acid-Gadolinium Coordination Polymer Nanorods for Improved Tumor Radioimmunotherapy by Synergetically Inducing Immunogenic Cell Death and Reprogramming the Immunosuppressive Microenvironment.

ACS Nano, 2021
Radiation therapy can potentially elicit a systemic immune response and cause the regression of nonirradiated tumors, and the checkpoint blockade immunotherapies have been introduced to improve their clinical response rate.
Zhusheng Huang, Dan Yao, Qingsong Ye, Haojie Jiang, Rong Gu, Changwei Ji, Jinhui Wu, Yiqiao Hu, A. Yuan   +8 more
semanticscholar   +1 more source

An Engineered Nanoplatform with Tropism Toward Irradiated Glioblastoma Augments Its Radioimmunotherapy Efficacy

Advances in Materials
Combining radiotherapy with immune checkpoint blockade therapy offers a promising approach to treat glioblastoma multiforme (GBM), yet challenges such as limited effectiveness and immune‐related adverse events (irAEs) persist.
Zheng Wang, Fangman Chen, Yi Cao, Fan Zhang, Lina Sun, Chao Yang, Xiaochun Xie, Ziping Wu, Madi Sun, F. Ma, Dan Shao, Kam W. Leong, Renjun Pei   +12 more
semanticscholar   +1 more source

Radioresponsive Delivery of Toll-like Receptor 7/8 Agonist for Tumor Radioimmunotherapy Enabled by Core-Cross-Linked Diselenide Nanoparticles.

ACS Nano
The development of a radioresponsive delivery platform has led to an innovative combination radioimmunotherapy strategy for treating tumors. However, controlling the release of immunomodulators by local radiotherapy in vivo remains a significant ...
Yanxian Wu, Jianzhong Qin, Yuan Gu, Gang Zhao, Pei Xu, Subin Lin, Xiaju Cheng, Leshuai W. Zhang, Yangyun Wang, Yong Wang   +9 more
semanticscholar   +1 more source

Particle radiotherapy in the era of radioimmunotherapy.

Cancer Letters, 2023
Zihan Zhou, B. Guan, Huang Xia, Rong Zheng, Benhua Xu   +4 more
semanticscholar   +1 more source

Radioimmunotherapy of solid tumors: Approaches on the verge of clinical application.

Journal of labelled compounds & radiopharmaceuticals, 2018
While radioimmunotherapy (RIT) for the treatment of hematological malignancies such as indolent B-cell lymphoma has proven quite successful, clinical results of RIT in solid tumors have only been moderate in the past. The reasons were manifold and can be
M. Bartholomä
semanticscholar   +1 more source

Novel antigens for targeted radioimmunotherapy in hepatocellular carcinoma

Molecular and Cellular Biochemistry, 2022
M. Pourhamzeh, Samieh Asadian, H. Mirzaei, Azita Minaei, Elahe Shahriari, A. Shpichka, Hamidreza Aboulkheyr Es, P. Timashev, Moustapha Hassan, Dr. Massoud Vosough   +9 more
semanticscholar   +1 more source