Results 231 to 240 of about 87,481 (331)

Emerging role of HIC1 in prostate cancer progression and therapeutic response: A novel perspective

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 4, December 2025.
HIC1 inhibits AR expression to suppress the development of castration‐resistant prostate cancer through the IRS2/PI3K/AKT axis. Abstract Prostate cancer (PCa) is a leading cause of cancer‐related death in men, with its progression and treatment response being complex. The study focuses on the role of HIC1 (Hypermethylated in cancer 1) in PCa, revealing
Dun Xue   +5 more
wiley   +1 more source

Radiolabeling molecular biomarkers of invasive pituitary adenomas: a narrative review. [PDF]

open access: yesPituitary
Marche C   +6 more
europepmc   +1 more source

Synthesis of Micro 14C‐Labeled Polylactide for Environmental Assessment Analysis

open access: yesChemistry–Methods, Volume 5, Issue 12, November 2025.
In this study, we present the production of 14C‐labeled PLA under optimized synthesis conditions. First, the industrially toxic catalyst Sn(Oct)2 was compared with an alternative, biocompatible zinc bisguanidine catalyst in the synthesis of lactide from lactic acid.
Sara Adeleh   +5 more
wiley   +1 more source

A Fast Path from Innovation to Safe and Effective Medicines

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1392-1404, December 2025.
Consistent progress in medicines development has allowed both for de novo treatment options and for the refinement of existing products that improve effectiveness or reduce harm. Nonetheless, unmet medical needs persist, particularly in rare diseases, pediatrics and underserved populations.
Peter Arlett   +11 more
wiley   +1 more source

Heat-induced radiolabeling and fluorescence labeling of Feraheme nanoparticles for PET/SPECT imaging and flow cytometry

open access: yesNature Protocols, 2018
Hushan Yuan   +5 more
semanticscholar   +1 more source

Predictive Factors of Malignancy in Cervical Paragangliomas: A Retrospective Study

open access: yesHead &Neck, Volume 47, Issue 12, Page 3340-3348, December 2025.
ABSTRACT Background Early predictive factors of metastatic cervical paragangliomas (cPG) are lacking. Methods This multicenter retrospective study included patients with at least one cPG. Metastatic cPG were defined by the histological presence of lymph node metastases or distant metastases.
Garance Haw   +13 more
wiley   +1 more source

Radiolabeling isolated mitochondria with Tc-99m: A first-in-field protocol and early feasibility findings. [PDF]

open access: yesBiol Methods Protoc
Walker M   +7 more
europepmc   +1 more source

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