Results 281 to 290 of about 87,481 (331)

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1245-1259, November 2025.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan   +5 more
wiley   +1 more source

Redefining AT1 Receptor PET Imaging: Introducing the Radiotracer [<sup>18</sup>F]DR29. [PDF]

open access: yesHypertension
Chen X   +11 more
europepmc   +1 more source

In vitro radionuclide labeling characteristics of blenderized tube feeds for quantitative gastric motility assessment

open access: yesJPGN Reports, Volume 6, Issue 4, Page 377-381, November 2025.
Abstract Gastric emptying scintigraphy (GES) using technetium‐99m‐sulfur colloid (99mTc‐SC) is an important tool for evaluating feeding intolerance. Stable 99mTc‐SC binding to the solid component of the meal is imperative for accurate result interpretation.
Bridget M. Hron   +7 more
wiley   +1 more source

Atypical Neuroblastoma With Absent Urinary Catecholamine Excretion and 123ImIBG Avidity Are of Favorable Outcome: A Retrospective French Single‐Center Study

open access: yesPediatric Blood &Cancer, Volume 72, Issue 11, November 2025.
Abstract Background In neuroblastoma (NB), urinary catecholamine excretion and 123ImIBG avidity—depending on tumor enzymatic activity and norepinephrine transporter expression, respectively—are diagnostic standards. The prognostic impact of atypical NB, without urinary catecholamine excretion and/or 123ImIBG avidity, remains to be determined. We sought
Anna Borovkov   +27 more
wiley   +1 more source

Expanding the Reach of Membrane Protein–Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics

open access: yesPROTEOMICS, Volume 25, Issue 21-22, Page 25-40, November 2025.
ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos   +3 more
wiley   +1 more source

Radiolabeling lipoproteins to study and manage disease. [PDF]

open access: yesEur J Nucl Med Mol Imaging
Pérez-Medina C   +4 more
europepmc   +1 more source

Amino acid substitutions at rheostat positions in the Na+/taurocholate cotransporting polypeptide substrate channel have pleiotropic effects

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract In the human Na+/taurocholate cotransporting polypeptide (NTCP), several non‐synonymous SNPs are known to have positive or negative medical consequences, and hundreds more are “variants of unknown significance.” One reason outcomes remain unknown is that computational predictions are not yet reliable.
Liskin Swint‐Kruse   +2 more
wiley   +1 more source

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