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Molecular Pharmaceutics, 2022
Molecular imaging with PET offers an alternative method to quantify programmed-death-ligand 1 (PD-L1) to accurately select patients for immunotherapies.
V. Tran +10 more
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Molecular imaging with PET offers an alternative method to quantify programmed-death-ligand 1 (PD-L1) to accurately select patients for immunotherapies.
V. Tran +10 more
semanticscholar +1 more source
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2022
In vivo measurements of the deposition of an inhaled radiolabeled pharmaceutic have provided useful information related to the inhaler efficiency for depositing drug in the lung. A number of labeling techniques have been developed and applied to pharmaceutical aerosols delivered by pressurized metered-dose inhalers (pMDIs), dry powder inhalers (DPIs ...
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In vivo measurements of the deposition of an inhaled radiolabeled pharmaceutic have provided useful information related to the inhaler efficiency for depositing drug in the lung. A number of labeling techniques have been developed and applied to pharmaceutical aerosols delivered by pressurized metered-dose inhalers (pMDIs), dry powder inhalers (DPIs ...
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Anchoring Group Mediated Radiolabeling for Achieving Robust Nanoimaging Probes.
Small, 2021Radiolabeling counts for much in the functionalization of inorganic nanoparticles (NPs) because it endows NPs with high-sensitive imaging capacities apart from providing accurate pharmacokinetic information on the labeled particles, which makes the ...
Lei Chen +6 more
semanticscholar +1 more source
, 2021
A new Tc-99m N-doped graphene quantum dot 99mTc-(N-GQD) moiety was developed as a radiolabeling agent for molecules lacking chelation or water solubility of ligands simultaneously. (N-GQDs) were synthesized and characterized with high purity (size range =
E. Gharepapagh +4 more
semanticscholar +1 more source
A new Tc-99m N-doped graphene quantum dot 99mTc-(N-GQD) moiety was developed as a radiolabeling agent for molecules lacking chelation or water solubility of ligands simultaneously. (N-GQDs) were synthesized and characterized with high purity (size range =
E. Gharepapagh +4 more
semanticscholar +1 more source
2013
Radioactive end-labeling is useful for visualizing and allowing the detection of nucleic acids at trace concentrations. Radioactive end-labeling can be carried out on RNA, DNA, or other modified nucleic acids. For RNA, the uses of end-labeling extend beyond simple detection of the intact RNA.
Rishi, Porecha, Daniel, Herschlag
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Radioactive end-labeling is useful for visualizing and allowing the detection of nucleic acids at trace concentrations. Radioactive end-labeling can be carried out on RNA, DNA, or other modified nucleic acids. For RNA, the uses of end-labeling extend beyond simple detection of the intact RNA.
Rishi, Porecha, Daniel, Herschlag
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Seminars in Nuclear Medicine, 1976
Bleomycin serves as a useful prototype for a study of the various properties required in a radiopharmaceutical for tumor imaging. Both in vitro and in vivo results using bleomycin labeled with a large number of different radionuclides have now been reported.
D A, Goodwin, C F, Meares
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Bleomycin serves as a useful prototype for a study of the various properties required in a radiopharmaceutical for tumor imaging. Both in vitro and in vivo results using bleomycin labeled with a large number of different radionuclides have now been reported.
D A, Goodwin, C F, Meares
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Radiolabeled Monoclonal Antibodies
AORN Journal, 1995ABSTRACTMonoclonal antibodies (MoAbs) are biologically engineered proteins designed to bind to antigens emanating from tumor cells. Selected radioactive isotopes are fused with MoAbs to allow radioimmunodetection or external imaging of metastatic deposits in patients with colon cancer.
C L, Brumley, J A, Kuhn
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Seminars in Nuclear Medicine, 1984
The radiolabeling of platelets has been studied for many years, both with megakaryocytes labeled in vivo and with direct platelet labels in vitro. The major aim of this work has been to evaluate platelet interactions in vivo. This has been made possible with indium-111-labeled platelets.
C J, Mathias, M J, Welch
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The radiolabeling of platelets has been studied for many years, both with megakaryocytes labeled in vivo and with direct platelet labels in vitro. The major aim of this work has been to evaluate platelet interactions in vivo. This has been made possible with indium-111-labeled platelets.
C J, Mathias, M J, Welch
openaire +2 more sources