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Radiolabeling strategies and pharmacokinetic studies for metal based nanotheranostics.

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2020
Radiolabeled metal-based nanoparticles (MNPs) have drawn considerable attention in the fields of nuclear medicine and molecular imaging, drug delivery, and radiation therapy, given the fact that they can be potentially used as diagnostic imaging and/or ...
S. Ranjbar Bahadori   +7 more
semanticscholar   +1 more source

Radiolabeling in Biology

Cell Biochemistry and Biophysics, 2014
Chemistry is the science of chemical reactions, the study of chemical properties, composition, and structure of a molecule. When the molecule under observation is of a biological origin (proteins, carbohydrates, lipids, or nucleic acids), the study of its chemical properties, reactions, and structure is known as biochemistry. Similarly, if the molecule
Xiaoying, Zhang   +2 more
openaire   +2 more sources

Radiolabeling strategies of micron- and submicron sized core-shell carriers for in vivo studies.

ACS Applied Materials and Interfaces, 2020
Core-shell particles made of calcium carbonate and coated with biocompatible polymers using Layer-by-Layer technique can be considered as a unique drug delivery platform that enables to load different therapeutic compounds, exhibits a high ...
M. Zyuzin   +11 more
semanticscholar   +1 more source

Radiolabelled chemotherapeutics.

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2007
During the past 3 decades various chemotherapeutics have been directly or indirectly radiolabeled for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging. Several of these radiolabeled chemotherapeutics have been injected into patients for the purpose of better understanding their biodistribution and ...
S. Rottey   +2 more
openaire   +4 more sources

Production of [89 Zr]Oxinate4 and cell radiolabeling for human use.

Journal of labelled compounds & radiopharmaceuticals, 2020
[89 Zr]Oxinate4 is a Positron Emission Tomography (PET) tracer for cell radiolabeling that can enable imaging techniques to help better understand cell trafficking in various diseases. Although several groups have synthetized this compound for use in pre-
Adriana V. F. Massicano   +8 more
semanticscholar   +1 more source

Radiolabelled human immunoglobulins

Nuclear Medicine Communications, 1995
Radiolabelled human immunoglobulins have been available for 5 years. Within that time there have been many publications on the use of these agents labelled with both technetium-99m (99Tcm) and indium-111 (111In). The results of these data appear contradictory and only now do we understand both some of the mechanisms of radiolabelled immunoglobulins and
openaire   +2 more sources

Calcium Bisphosphonate Nanoparticles with Chelator-Free Radiolabeling to Deplete Tumor-Associated Macrophages for Enhanced Cancer Radioisotope Therapy.

ACS Nano, 2018
Tumor-associated macrophages (TAMs) are often related with poor prognosis after radiotherapy. Depleting TAMs may thus be a promising method to improve the radio-therapeutic efficacy.
Longlong Tian   +8 more
semanticscholar   +1 more source

Rapid chelator-free radiolabeling of quantum dots for in vivo imaging.

Nanoscale, 2019
Most current nanoparticle-based PET tracers are radiolabeled through metal chelators conjugated on the nanoparticle surface. Metal chelation usually requires sophisticated optimization and may impact the physical or chemical properties of nanoparticles ...
Tang Tang   +5 more
semanticscholar   +1 more source

Anchoring Group-Mediated Radiolabeling of Inorganic Nanoparticles─A Universal Method for Constructing Nuclear Medicine Imaging Nanoprobes.

ACS Applied Materials and Interfaces, 2022
Jianxian Ge   +11 more
semanticscholar   +1 more source

Facile radiolabeling optimization process via design of experiments and an intelligent optimization algorithm: Application for omeprazole radioiodination.

Journal of labelled compounds & radiopharmaceuticals, 2019
The major uses of radiopharmaceuticals (RP) in clinical areas are diagnosis and/or therapy. The present study aimed to utilize the application of fractional factorial design analysis (FFDA) coupled with particle swarm optimization algorithm (PSO) to ...
N. Farrag   +2 more
semanticscholar   +1 more source

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