Results 101 to 110 of about 3,259,253 (212)

AChBPs expressed in E. coli are functional.

, 2016
Competitive radioligand binding assay with [3H]-epibatidine and nAChR ligands were used to determine the activity of (A) Ls-AChBP and (B) Ac-AChBP.
Nikita Abraham (1639795), Lotten Ragnarsson (394253), Richard J. Lewis (30801), Blessy Paul (1639783)   +3 more
core   +1 more source

When a Prophecy comes True: Ethyleneoxynitazene as a ‘Prophetic’ Member of the Emerging Class of 2-Benzylbenzimidazole ‘Nitazene’ Synthetic Opioids

Emerging Trends in Drugs, Addictions, and Health
Introduction: 2-Benzylbenzimidazole opioids (‘nitazenes’) have become increasingly prevalent on the recreational drug market. We performed pharmacological characterization of various 'prophetic' nitazenes, allowing risk prioritization based on structure ...
M.M. Vandeputte, G.C. Glatfelter, D. Walther, I. Ujváry, D.M. Iula, M.H. Baumann, C.P. Stove   +6 more
doaj   +1 more source

Novel Potent and Selective Dopamine D4 Receptor Piperidine Antagonists as Potential Alternatives for the Treatment of Glioblastoma

Pharmaceuticals
Background/Objectives: D4R antagonists have recently been suggested as potential therapeutic alternatives to the standard treatments of glioblastoma (GBM).
Federica Matteucci, Pegi Pavletić, Alessandro Bonifazi, Rian Garland, Hideaki Yano, Consuelo Amantini, Laura Zeppa, Emanuela Sabato, Giulio Vistoli, Valerio Mammoli, Loredana Cappellacci, Fabio Del Bello, Gianfabio Giorgioni, Riccardo Petrelli, Alessia Piergentili, Wilma Quaglia, Alessandro Piergentili   +16 more
doaj   +1 more source

Optimized conditions for radioligand binding and functional assays.

, 2019
Optimized conditions for radioligand binding and functional assays.
Daniel Womer (6807767), John M. Streicher (503153), Keith M. Olson (1484329), David I. Duron (6807764), Ryan Fell (6807770)   +4 more
core   +1 more source

LABELING OF DOPAMINE D3 AND D4 RECEPTOR SUBTYPES IN HUMAN PERIPHERAL BLOOD LYMPHOCYTES WITH [3H]7-OH-DPAT: A COMBINED RADIOLIGAND BINDING ASSAY AND IMMUNOCHEMICAL STUDY

, 1998
Molecular biology studies have demonstrated that human peripheral blood lymphocytes express dopamine D2-like receptors belonging to the D3 and D4 receptor subtypes, whereas the characterization of these receptors using radioligand binding assay ...
GRECO S., AMENTA, Francesco, FELICI L., RICCI A., BRONZETTI E.   +4 more
core   +1 more source

In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand

, 2011
In this study, we evaluated the in vivo characteristics of a new monoamine oxidase type B (MAO-B) radioligand, [¹⁸F]fluorodeprenyl, by positron emission tomography (PET) in two cynomolgus monkeys. The brain uptake of [¹⁸F]fluorodeprenyl was more than 7% (
Thiele, Andrea, Lehmann, Lutz, Nag, Sangram, Varrone, Andrea, Halldin, Christer, Tóth, Miklós, Andrea Thiele, Andrea Varrone, Heinrich, Tobias, Tobias Heinrich, MiklÓs TÓth, Christer Halldin, Georg Kettschau, Kettschau, Georg, Sangram Nag, Lutz Lehmann, Kettschau, G, Nag, S,, Halldin, C,, Thiele, A, Lehmann, L, Varrone, A,, Lehmann, Lutz Eric, Toth, M,, Heinrich, T   +24 more
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Labelling of dopamine D3 and D4 receptor subtypes in human peripheral blood lymphocytes with [3H]7-OH-DPAT: a combined radioligand binding assay and immunochemical study.

, 1998
Molecular biology studies have demonstrated that human peripheral blood lymphocytes express dopamine D2-like receptors belonging to the D3 and D4 receptor subtypes, whereas the characterization of these receptors using radioligand binding assay ...
AMENTA, Francesco
core   +1 more source

Muscarinic receptor activity of some Malaysian plant species

, 2005
Muscarinic receptor binding activity was tested on 224 plant extracts obtained from more than 50 plant families found in Malaysia. The plant extracts were evaluated by a 96-well microplate filtration–based radioligand competitive assay, centered on ...
Chung, L.Y., Yap, K.F., Goh, S.H., Imiyabir, Z., Mustafa, Mohd Rais   +4 more
core   +2 more sources

A new approach to cytochrome CYP2D6 antibody detection in autoimmune hepatitis type‐2 (AIH‐2) and chronic hepatitis C virus (HCV) infection: a sensitive and quantitative radioligand assay

Clinical and Experimental Immunology, 1997
A. Yamamoto, C. Johanet, J. Duclos-Vallée, F. A. Bustarret, Fernando Alvarez, J. Homberg, Jean-François Bach   +6 more
semanticscholar   +1 more source

¹⁷⁷Lutetium PSMA radioligand therapy for the treatment of metastatic castrate-resistant prostate cancer: Evidence synthesis to support a generic justification decision

This review was conducted in response to an application submitted by a radiologist at the Mater Misericordiae University Hospital for the generic justification of lutetium (177Lu) prostate-specific membrane antigen (PSMA) radioligand therapy for the ...
Health Information and Quality Authority (HIQA)
core