Results 91 to 100 of about 73,359 (292)

Fractal Anatomy of Human Organs: A Narrative Review of Structure, Function, and Clinical Perspectives

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Fractal geometry describes complex, self‐similar patterns that repeat across spatial scales and is increasingly recognized as relevant in anatomical research. Indeed, the fractal organization is consistently observed in respiratory, cardiovascular, gastrointestinal, nervous, renal, hepatic, and dermatological systems.
Immacolata Belviso   +7 more
wiley   +1 more source

Porous Organic Frameworks‐Based Nanomaterials in Colorectal Cancer Therapy: From Drug Delivery to Personalized Nano‐Vaccine

open access: yesCancer Nexus, EarlyView.
ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song   +3 more
wiley   +1 more source

Validity of a multiphase CT-based radiomics model in predicting the Leibovich risk groups for localized clear cell renal cell carcinoma: an exploratory study

open access: yesInsights into Imaging, 2023
Objective To develop and validate a multiphase CT-based radiomics model for preoperative risk stratification of patients with localized clear cell renal cell carcinoma (ccRCC).
Huayun Liu   +8 more
doaj   +1 more source

340P Prediction of relapse in colon cancer patients by machine learning models combining radiomics and deep features extracted from baseline computed tomography [PDF]

open access: bronze, 2022
A. Bueno Gómez   +13 more
openalex   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Genomic signature driving preinvasive to invasive processes in stage I lung adenocarcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The progression of lung cancer from minimally invasive adenocarcinoma (MIA) to invasive adenocarcinoma (IA) is a complex process involving molecular and microenvironment changes. Key molecular events that drive the invasion process, however, remain poorly characterized. In this comparison of gene profiles and differentially mutated genes in
Biqin Mou   +19 more
wiley   +1 more source

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval   +8 more
wiley   +1 more source

PelviSound L—Real‐time intraoperative sonographic assessment of pelvic sentinel lymph nodes using a drop‐in probe in endometrial and cervical cancer during minimally invasive surgery: A single‐center pilot feasibility study in 20 patients

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Sentinel lymph node biopsy (SLNB) is considered an essential step in the surgical management of endometrial and cervical cancers as it has led to a reduction in the need for full pelvic lymphadenectomy. This proof‐of‐concept study aimed to evaluate the feasibility and diagnostic performance of intraoperative sonographic assessment of
Sascha Hoffmann   +7 more
wiley   +1 more source

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