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Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer [PDF]

open access: yesCancer Innovation
In recent years, multidisciplinary treatment strategies have profoundly improved drug responses and survival outcomes of breast cancer (BC) patients. However, there is an urgent need for novel therapies for BC patients who are heavily treated or develop ...
Yujing Tan   +3 more
doaj   +2 more sources

Assessing the radiation-induced bystander effect in radionuclide therapy using targeted radiopharmaceuticals [PDF]

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Radiation-induced biologic bystander effects (RIBBEs) where non-irradiated cells display radiation like responses are well established in the context of external beam radiotherapy.
Rohit Sharma   +3 more
doaj   +2 more sources

Optimization of radiation protection in radionuclide therapy: Proposals for developing quality assurance programs

open access: diamondРадиационная гигиена
In order to ensure a high-quality and safe therapeutic process in radionuclide therapy, it is not sufficient to rely solely on safety monitoring within the framework of production control. Measures must be implemented within a quality assurance system as
A. V. Likhacheva   +2 more
doaj   +3 more sources

Association of regional cerebral perfusion impairment with gait and balance performance in dizzy patients using brain perfusion SPECT: Voxel-based analysis of a pilot sample [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2021
Objective(s): The purpose of this study was to investigate regional cerebral blood flow (rCBF) reduction in patients with dizziness and perfusion-related clinical impairment using brain perfusion single photon emission tomography (SPECT).Methods: Thirty ...
Reza Nemati   +7 more
doaj   +1 more source

Radiometals in Imaging and Therapy: Highlighting Two Decades of Research

open access: yesPharmaceuticals, 2023
The present article highlights the important progress made in the last two decades in the fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based positron emission tomography, single photon emission computerized tomography,
Shalini Sharma, Mukesh K. Pandey
doaj   +1 more source

Improvement of the approach to definition of patient release criteria after radionuclide therapy

open access: yesРадиационная гигиена, 2023
Current patient release criteria established in NRB-99/2009 relate to four radionuclides used in Russia that period of the document preparation. These criteria were calculated only considering the radionuclide decay.
L. A. Chipiga   +7 more
doaj   +1 more source

Recent Advances in Hepatocellular Carcinoma Treatment with Radionuclides

open access: yesPharmaceuticals, 2022
As the third leading cause of cancer death worldwide, hepatocellular carcinoma (HCC) is characterized by late detection, difficult diagnosis and treatment, rapid progression, and poor prognosis.
Ruiqi Liu   +4 more
doaj   +1 more source

A brief overview of targeted radionuclide therapy trials in 2022

open access: yesFrontiers in Nuclear Medicine, 2023
There is a growing use of radionuclide therapy for the medical care of oncology patients, where radioactive pharmaceuticals are used to target and treat various cancer types.
Aidan Healy   +3 more
doaj   +1 more source

An overview on prostate-specific membrane antigen uptake in malignancies other than prostate cancer: A pictorial essay

open access: yesWorld Journal of Nuclear Medicine, 2020
Prostate-specific membrane antigen (PSMA) is a Type II transmembrane glycoprotein which is extremely overexpressed in prostate cancer epithelial cells. Recently, PSMA-targeted small molecule labeled with 68Ga and 99mTc allowed precise molecular imaging ...
Esmail Jafari   +3 more
doaj   +1 more source

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