Results 171 to 180 of about 58,904 (306)

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen   +8 more
wiley   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou   +17 more
wiley   +1 more source

TP53 ‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, Volume 100, Issue S4, Page 88-115, June 2025.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53 mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah   +2 more
wiley   +1 more source

Guideline for the Management Pathway and Quality Control of Breast Cancer Prevention and Treatment in China's Counties

open access: yesCancer Innovation, Volume 4, Issue 3, June 2025.
County hospitals bear the primary responsibility for health education, screening, primary diagnosis and treatment, maintenance treatment, management of adverse reactions to antitumor drugs, patient follow‐up, recurrence monitoring, rehabilitation guidance, and two‐way referrals for breast cancer.
Breast Cancer Expert Committee of National Cancer Quality Control Center   +1 more
wiley   +1 more source

Lead-212 Radiopharmaceuticals for Receptor-Targeted Radionuclide Therapy [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Receptor-targeted radionuclide therapy (RTRT) combines the power of particle-emitting radionuclides with the receptor-targeting capabilities of biomolecules, including antibodies and peptides.
Solmaz Mojarad-Jabali   +1 more
doaj  

Collimator-less SPECT System Design for Dynamic Whole-body Imaging [PDF]

open access: yesarXiv
In this study, we introduce a Compton SPECT system for whole-body imaging of Actinium-225 (225Ac), one of the trending radionuclides for targeted alpha therapy (TAT). The Compton SPECT system enables multi-energy gamma photon detection with higher efficiency compared to mechanically collimated SPECT.
arxiv  

αvβ3 Integrin‐targeting radionuclide therapy and imaging with monomeric RGD peptide [PDF]

open access: bronze, 2008
Mitsuyoshi Yoshimoto   +6 more
openalex   +1 more source

Gastric Myoelectrical Activity Patterns and Water‐Load Satiety Test in Patients With Chronic Dyspeptic Symptoms

open access: yesJGH Open, Volume 9, Issue 6, June 2025.
ABSTRACT Background/Aims Patients with chronic dyspeptic symptoms may or may not experience nausea and vomiting. Consensus papers suggested that gastroparesis should be defined by symptoms like nausea and vomiting rather than investigations only. Recognizing that gastric dysrhythmias contribute to nausea, vomiting, and maybe a biomarker and therapeutic
Uday C. Ghoshal   +9 more
wiley   +1 more source

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