Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John+5 more
core +1 more source
Fast full patient and radioisotope Monte Carlo simulations of targeted radionuclide therapy: introducing egs_mird [PDF]
BACKGROUND: Targeted Radionuclide Therapy (TRT) is a fast-growing field garnering much interest, however, dosimetry calculation techniques remain relatively simple. PURPOSE: To introduce egs_mird, a new Monte Carlo application built in EGSnrc which allows users to model full patient tissue and density (using clinical CT images) and radionuclide ...
arxiv
Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection [PDF]
Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection.
Bron, K+8 more
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USE OF 177Lu-PSMA FOR RADIONUCLIDE THERAPY IN PATIENTS WITH CASTRATE-RESISTANT PROSTATE CANCER
Purpose of the study: to present current data regarding challenges in treatment of castration-resistant prostate cancer (CRPC) and the relationship between CRPC and the expression of prostate-specific membrane antigen (psma).Material and Methods.
A. A. Medvedeva+5 more
doaj +1 more source
Stem Cell Imaging: Tools to Improve Cell Delivery and Viability. [PDF]
Stem cell therapy (SCT) has shown very promising preclinical results in a variety of regenerative medicine applications. Nevertheless, the complete utility of this technology remains unrealized. Imaging is a potent tool used in multiple stages of SCT and
Jokerst, Jesse V, Wang, Junxin
core +3 more sources
Measurement of Ac227 Impurity in Ac225 using Decay Energy Spectroscopy [PDF]
225Ac is a valuable medical radionuclide for targeted alpha therapy, but 227Ac is an undesirable byproduct of an accelerator-based synthesis method under investigation. Sufficient detector sensitivity is critical for quantifying the trace impurity of 227Ac, with the 227Ac/225Ac activity ratio predicted to be approximately 0.15% by end-of-bombardment ...
arxiv
99mTc-DTPA and 131I-hippuran findings in liver transplant recipients treated with cyclosporin A. [PDF]
The effects of cyclosporin A (CyA), an immunosuppressive agent that is potentially nephrotoxic, on the kidneys of 9 liver transplant recipients were studied with serial 99mTc-DTPA and 131I-hippuran scans.
Iwatsuki, S+4 more
core +1 more source
Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group [PDF]
Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established.
Badalamenti, G.+17 more
core +1 more source
Nuclear medicine and molecular imaging in clinical practice: yesterday, today and tomorrow
Over the past 40 years, nuclear medicine has grown to be the largest non-invasive diagnostic and therapeutic industry in the world, playing a pivotal role in various fields and disciplines of clinical practice and contributing to improved quality of life
Vladimir B. Sergienko+1 more
doaj +1 more source
The expanding role of nuclear medicine in therapeutic strategies [PDF]
The concept of carrying a cytotoxic radionuclide directly to cancerous cells is an attractive alternative to conventional forms of radiation treatment.
Aquilina, Mark Anthony
core