Results 81 to 90 of about 30,778 (256)

Recommendations for bone‐directed therapy in patients with neuroendocrine tumour skeletal metastases at the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting

open access: yesInternal Medicine Journal, EarlyView.
Abstract The role of anti‐resorptive agents in patients with bone metastases from neuroendocrine neoplasms is unclear. Our aim was to review bone‐specific treatment recommendations by the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting (MDM).
Gayle Radley   +3 more
wiley   +1 more source

Prospects in folate receptor-targeted radionuclide therapy

open access: yesFrontiers in Oncology, 2013
Targeted radionuclide therapy is based on systemic application of particle-emitting radiopharmaceuticals which are directed towards a specific tumor-associated target. Accumulation of the radiopharmaceutical in targeted cancer cells results in high doses
Cristina eMüller   +2 more
doaj   +1 more source

Combined VLA-4–Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma [PDF]

open access: bronze, 2018
Jae‐Yeon Choi   +7 more
openalex   +1 more source

Yeast‐Based Biotechnology for Civilian Security

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała   +2 more
wiley   +1 more source

Design of Stimuli‐Responsive Cobalt Tetraphenylporphyrinate‐Chitosan Microspheres for Advanced Biosensors

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 3, January 21, 2026.
We report on new cobalt tetraphenylporphyrinate‐chitosan‐based microspheres developed for biosensing and anticancer therapy applications. We analyzed their second‐harmonic generation (SHG) behavior using a high‐resolution SHG microscope. In addition to the typical porphyrinate fluorescence, the microspheres exhibit a high‐intensity SHG response and ...
Domenica Marabello   +8 more
wiley   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, Volume 36, Issue 2, 5 January 2026.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Effects of Prior Local Therapy by Radical Prostatectomy or Radiotherapy on the Efficacy and Quality of Life of Patients Treated With Darolutamide in ARAMIS

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Darolutamide plus androgen‐deprivation therapy (ADT) improved metastasis‐free survival (MFS) by 2 years and reduced the risk of death by 31% in nonmetastatic castration‐resistant prostate cancer (nmCRPC) in ARAMIS. Prior local therapy may influence the efficacy of subsequent systemic therapy.
Matthias Saar   +18 more
wiley   +1 more source

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