Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang +11 more
wiley +1 more source
Contemporary opportunities and potential of Auger electron-emitting theranostics. [PDF]
Lee SY, Manning HC.
europepmc +1 more source
25 Years of “Loop” Radiochemistry for PET Imaging
While conventional methods to 11C‐ and 18F‐labelled radiopharmaceuticals utilize a vial‐based approach, in the past quarter‐century, a modern, efficient, and cleaner “loop method” has been developed. The radiochemical diversity of reactions synthesized by the loop method are shown.
Emily Murrell, Sahil Khan, Neil Vasdev
wiley +1 more source
Radiological risk assessment of natural radioactivity in imported rice consumed in Ghana and its implications for food safety and public health. [PDF]
Dickson-Agudey P +7 more
europepmc +1 more source
Antibody–Drug Conjugates in Oncology: Principles, Clinical Development, and Future Directions
Antibody–drug conjugates integrate antibody targeting with potent cytotoxic payloads to enable precision cancer therapy. Their clinical performance depends on coordinated optimization of engineering design, tumor antigen biology, and treatment strategy. Lessons from uro‐oncological malignancies illustrate how ADCs can be effectively developed, combined,
Bisheng Cheng +6 more
wiley +1 more source
Maternal geophagy in Ghana: a mini review of toxicological, microbial, nutritional, and radiological exposure pathways. [PDF]
Lawluvi H +6 more
europepmc +1 more source
Targeted Therapies for Each Subtype of Breast Cancer
This review systematically summarizes the advances in targeted therapies for the three major molecular subtypes of breast cancer (BC), highlighting key strategies, agents, and clinical progress to guide personalized treatment. HR‐positive (luminal) BC: Dominated by estrogen receptor (ER) signaling, with endocrine therapies as the cornerstone—including ...
Aiyu Liu +5 more
wiley +1 more source
Radiological Hazard Assessment of Soil at North Oil Company Using Spatial Distribution and Monte Carlo Simulation in Kirkuk Governorate, Iraq. [PDF]
Namq BF, Wais TY.
europepmc +1 more source
Abstract Background Independent verification of the manufacturer‐provided dosimetry data for 106Ru ophthalmic brachytherapy applicators is crucial for safe and accurate treatment, yet a standardized, traceable method for clinical absolute dosimetry has been lacking. Purpose This work establishes a complete framework for traceable absorbed dose to water
Simon Dahlander +5 more
wiley +1 more source

