Results 141 to 150 of about 22,462 (308)

Novel Direct Alpha Spectroscopy Technique for $^{225}$Ac Radiopharmaceutical detection in Cancer Cells [PDF]

open access: yesarXiv
Targeted alpha-particle therapy (TAT) employs alpha-emitting radionuclides conjugated to tumor-targeting molecules to deliver localized radiation to cancer cells, showing great promise in treating metastatic cancers. Among these radionuclides, Actinium-225 ($^{225}$Ac, t$_{1/2}$ = 9.9 days) has emerged as a clinically promising candidate.
arxiv  

Expert panel on monitoring radiation doses from recurrent medical diagnostic procedures: Sixth Gilbert W. Beebe Webinar

open access: yesJournal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Recurrent imaging is an essential tool for patient care but with an attendant dose from radiation exposure. Recurrent imaging has been the subject of increasing scrutiny and debate based largely on the risk from increasing cumulative doses. However, the accountability for and actions with recurrent imaging as a special component in the general
Donald P. Frush   +8 more
wiley   +1 more source

Semi-Supervised Learning for Dose Prediction in Targeted Radionuclide: A Synthetic Data Study [PDF]

open access: yesarXiv
Targeted Radionuclide Therapy (TRT) is a modern strategy in radiation oncology that aims to administer a potent radiation dose specifically to cancer cells using cancer-targeting radiopharmaceuticals. Accurate radiation dose estimation tailored to individual patients is crucial.
arxiv  

Study on Tumor Affinity of 99mTc-labeled Radiopharmaceuticals

open access: bronze, 1977
Kazuo Itoh   +4 more
openalex   +2 more sources

Evaluating auto‐contouring accuracy in reduced CT dose images for radiopharmaceutical therapies: Denoising and evaluation of 177Lu DOTATATE therapy dataset

open access: yesJournal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Purpose Reducing radiation dose attributed to computed tomography (CT) may compromise the accuracy of organ segmentation, an important step in 177Lu DOTATATE therapy that affects both activity and mass estimates. This study aimed to facilitate CT dose reduction using deep learning methods for patients undergoing serial single photon emission ...
Hung‐Te Yang   +2 more
wiley   +1 more source

Alzheimer's disease—Biomarkers, clinical evaluation or both?

open access: yes
Journal of Neuropsychology, EarlyView.
Joel Simrén   +3 more
wiley   +1 more source

Generation of Site‐Specifically Labeled Affinity Reagents via Use of a Self‐Labeling Single Domain Antibody

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
Several methods have been used to label antibodies to facilitate visualization of cognate targets. Here, we leverage a new variety of conjugation chemistry, based on a crosslinking nanobody, to label target‐specific nanobody constructs with functionalities of choice.
Stanley Fayn   +12 more
wiley   +1 more source

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