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, 2023 Ce document est la propriété de l'IRSN et ne peut être communiqué, reproduit ou utilisé sans son autorisation écrite préalable. - This document is the property of IRSN and shall not be disseminated, copied or used without its prior formal approval ...
Institut de Radioprotection et de Sûreté Nucléaire, [IRSN]
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Cobalt Single-Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation. [PDF]
Adv Sci (Weinh)Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Yin S +13 more
europepmc +2 more sources
RESONANCE EVALUATION OF 239Pu IN THE RESONANCE REGION UP TO 4 keV [PDF]
EPJ Web of Conferences, 2021 Resolved resonance evaluation of the 239Pu cross section in the energy range up 4 keV has been carried out with the SAMMY computer code. Existing resolved resonance evaluation such as ENDF/B-VIII.0 and JENDL4 data libraries for 239Pu is limited to 2.5 ...
Leal Luiz +2 more
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Stem Cell Research & Therapy, 2023 Background Cellular therapy seems to be an innovative therapeutic alternative for which mesenchymal stem cells (MSCs) have been shown to be effective for interstitial and hemorrhagic cystitis.
Clément Brossard +10 more
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Exploration of genetic algorithms to build a balanced neutron spectra dataset useful to train unfolding techniques based on artificial neural networks [PDF]
EPJ Web of ConferencesDiverse domains need neutrons unfolding technics to assess the incident neutron energy spectrum. Examples are radiation protection, nuclear reactor physics or criticality safety.
Bouhadida Maha +6 more
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, 2021 International audienceL'article présente la radioprotection dans un dictionnaire en ergonomie. Après une présentation des principales notions, l'article souligne les liens qui existent entre radioprotection et ergonomie des situations de ...
Lecomte, Jean Francois +1 more
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Gene therapy for radioprotection [PDF]
Cancer Gene Therapy, 2015 Radiation therapy is a critical component of cancer treatment with over half of patients receiving radiation during their treatment. Despite advances in image-guided therapy and dose fractionation, patients receiving radiation therapy are still at risk for side effects due to off-target radiation damage of normal tissues. To reduce normal tissue damage,
W H, Everett, D T, Curiel
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MEASUREMENT, EVALUATION AND VALIDATION OF MOLYBDENUM CROSS SECTIONS [PDF]
EPJ Web of Conferences, 2021 Available nuclear data for molybdenum included in the nuclear data libraries are not of sufficient quality for reactor physics or criticality safety issues and indeed information about uncertainties and covariance is either missing or leaves much to be ...
Duhamel Isabelle +4 more
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Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action. [PDF]
PLoS ONE, 2015 ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. These two classes of drug act by curtailing the actions of angiotensin II-linked inflammatory pathways ...
Hong Wang +3 more
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Organoids in Precision Radiotherapy: Methodological Foundations, Tumor-Specific Evidence, and Translational Roadmaps. [PDF]
Cancer MedABSTRACT Background Radiotherapy remains a cornerstone of cancer treatment, while its efficacy is often limited by tumor radioresistance and the risk of normal tissue toxicity. Conventional preclinical models, including two‐dimensional (2D) cell cultures and murine xenografts, exhibit significant limitations in recapitulating human tumor ...
Zhu Y, Jiao Y, Xue J, Lv X, Qin S.
europepmc +2 more sources