Results 221 to 230 of about 27,469 (292)

Evaluating deposited radiation energy amount and collision quantities of small-molecule radiosensitizers through Monte Carlo simulations. [PDF]

Heliyon
ALMisned G, Kilic CS, Almansoori A, Mesbahi A, Hamad M, Tekin HO.   +5 more
europepmc   +1 more source

Gold Nanoparticles as a Potent Radiosensitizer: A Transdisciplinary Approach from Physics to Patient

Cancers, 2020
Over the last decade, a growing interest in the improvement of radiation therapies has led to the development of gold-based nanomaterials as radiosensitizer. Although the radiosensitization effect was initially attributed to a dose enhancement mechanism,
Sébastien Penninckx, Anne-Catherine Heuskin, Carine Michiels   +2 more
exaly   +2 more sources

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Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma

Biomaterials, 2022
Chemoradiotherapy is a widely used treatment for patients with malignancies such as hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and synergistic chemotherapy and radiation sensitization.
Yupeng Wang, Yue Pan
exaly   +2 more sources

Tumor Microenvironment Modulation Platform Based on Composite Biodegradable Bismuth–Manganese Radiosensitizer for Inhibiting Radioresistant Hypoxic Tumors

Small, 2021
Solid tumors possess a unique internal environment with high-level thiols (mainly glutathione), over-expressed H2 O2 , and low oxygen partial pressure, which severely restrict the radiotherapy (RT) efficacy.
Ruizhuo Ouyang, Yuqing Miao, Yun Sun
exaly   +2 more sources

Nanozyme-Incorporated Biodegradable Bismuth Mesoporous Radiosensitizer for Tumor Microenvironment-Modulated Hypoxic Tumor Thermoradiotherapy

ACS Applied Materials & Interfaces, 2020
Solid tumors inevitably develop radioresistance due to low oxygen partial pressure in the tumor microenvironment. Despite numerous attempts, there are still few effective ways to avoid the hypoxia-induced poor radiotherapeutic effect.
Ruizhuo Ouyang, Yuqing Miao, Yun Sun
exaly   +2 more sources

Results of Phase III Randomized Trial for Use of Docetaxel as a Radiosensitizer in Patients With Head and Neck Cancer, Unsuitable for Cisplatin-Based Chemoradiation

Journal of Clinical Oncology, 2023
PURPOSE There is a lack of published literature on systemic therapeutic options in cisplatin-ineligible patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC) undergoing chemoradiation.
V. Patil, V. Noronha, N. Menon, A. Singh, S. Ghosh-Laskar, A. Budrukkar, A. Bhattacharjee, M. Swain, V. Mathrudev, K. Nawale, A. Balaji, Z. Peelay, Mitali Alone, Shruti Pathak, A. Mahajan, Suman Kumar, N. Purandare, A. Agarwal, A. Puranik, Shantanu J. Pendse, Monica Reddy Yallala, Harsh Sahu, Venkatesh Kapu, Sayak Dey, Jatin Choudhary, M. R. Krishna, Alok Shetty, Naveen Karuvandan, R. Ravind, R. Rai, K. Jobanputra, P. Chaturvedi, P. Pai, D. Chaukar, S. Nair, S. Thiagarajan, K. Prabhash   +36 more
semanticscholar   +1 more source

Engineering Radiosensitizer‐Based Metal‐Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy

Advances in Materials, 2021
Radiotherapy, a mainstay of first‐line cancer treatment, suffers from its high‐dose radiation‐induced systemic toxicity and radioresistance caused by the immunosuppressive tumor microenvironment.
Jie Yan, Guohao Wang, Lisi Xie, Hao Tian, Jie Li, Bei Li, Wei Sang, Wenxi Li, Zhan Zhang, Yunlu Dai   +9 more
semanticscholar   +1 more source

Designing Bimetallic Metal‐Organic Framework‐Based Heterojunction Radiosensitizer for Enhanced Radiodynamic Therapy and Immunotherapy

Advanced Functional Materials, 2023
Radiotherapy, as one of the most common strategies for clinical cancer treatment, suffers from failure due to the hypoxia, inflammation, and radiosensitivity difference of malignant tumors, side effects, and radioresistance.
Zushuang Xiong, Mingqi Yang, Peixin Liu, Zhiying Tang, Y. Yang, Meixiao Zhan, T. Chen, Xiaoling Li, Ligong Lu   +8 more
semanticscholar   +1 more source