Results 241 to 250 of about 27,469 (292)
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An Atomically Precise Gold-Levonorgestrel Nanocluster as a Radiosensitizer for Enhanced Cancer Therapy.

ACS Nano, 2019
Gold nanoclusters have become promising radiosensitizers due to their ultrasmall size and robust ability to adsorb, scatter and re-emit radiation. However, most of the previously reported gold nanocluster radiosensitizers do not have a precise atomic ...
Tongtong Jia   +10 more
semanticscholar   +1 more source

Preparation, characterization and in vitro evaluation of magnesium ferrite superparamagnetic nanoparticles as a novel radiosensitizer of breast cancer cells

, 2020
One of the noble ways to increase the efficacy of radiotherapy (RT) is to use nanoparticles (NPs) as radiosensitizers and this can be too much attractive for researchers.
A. Meidanchi, Anna Motamed
semanticscholar   +1 more source

Facile synthesis of Bi2S3-MoS2 heterogeneous nanoagent as dual functional radiosensitizer for triple negative breast cancer theranostics

, 2020
The radioresistance of tumor cells is considered to be a major factor responsible for the clinical failure of radiotherapy. Instead of simply increasing the radiation dose, effective elevation the tumor radiosensitivity is an alternative strategy for ...
Fei Gao   +11 more
semanticscholar   +1 more source

Ultraeffective Cancer Therapy with an Antimonene‐Based X‐Ray Radiosensitizer

Advanced Functional Materials, 2019
Nanoparticulate chemotherapeutics hold great potential for inducing reactive oxygen species (ROS) overproduction and exerting antihypoxic effects for efficient cancer radiotherapy.
Yanhong Duo   +6 more
semanticscholar   +1 more source

Care with radiosensitizers

The British Journal of Radiology, 1979
Hendry and Sutton (1978) express concern about the possible sensitizing effect of misonidazole in normal tissues in patients treated with this drug combined with radiotherapy. Their argument is based upon the enhanced effect seen in human normal tissues following treatment in hyperbaric oxygen and upon observations in animals when radiotherapy is ...
G E, Adams, S, Dische
openaire   +2 more sources

Organelle-localized radiosensitizers

Chemical Communications, 2020
This feature article highlights the recent advances of organelle-localized radiosensitizers and discusses the current challenges and future directions.
Yuanyuan Chen   +5 more
openaire   +2 more sources

[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer].

Gan no rinsho. Japan journal of cancer clinics, 1991
Because of the unsuccessful clinical trials of misonidazole (MISO), many efforts have been made to find a new hypoxic cell sensitizer which is more effective and/or less toxic than MISO. In Japan, RK-28 is already under going Phase II clinical evaluation and RP-170, KU-2285 and KIH-802 have been proven to be effective both in vitro and in vivo and are ...
C, Murayama, T, Mori
openaire   +1 more source

Modifiers of radiosensitivity

Experientia, 1989
Many different methods exist by which the radiosensitivity of cells, and hence of normal tissues and tumours, can be manipulated. Several of these can be traced to a common redox pathway involving competition between oxidising and reducing species. Others involve the biochemical enzyme systems required for removal of DNA lesions.
A, Rojas, J, Denekamp
openaire   +2 more sources

Taxanes as radiosensitizers

Anti-Cancer Drugs, 2014
In parallel with the discovery of the taxanes, our understanding of the molecular underpinnings that comprise the classic biologic principles of fractionated radiotherapy has rapidly evolved over the past half century. Early studies have implicated DNA as the primary target for radiation-induced lethality.
Encouse B, Golden   +2 more
openaire   +2 more sources

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