Results 251 to 260 of about 27,469 (292)

A nuclear-targeted titanium dioxide radiosensitizer for cell cycle regulation and enhanced radiotherapy.

Chemical Communications, 2019
A nuclear-targeted titanium dioxide radiosensitizer was developed to regulate the cell cycle and enhance the radiation effect.
W. Pan, Shaohua Gong, Jianbo Wang, Longhai Yu, Yuanyuan Chen, Na Li, B. Tang   +6 more
semanticscholar   +1 more source

Radioprotection by Radiosensitizers

1977
The title to this paper was chosen to point deliberately upon the semantic problem involved in characterizing modifications of the response to radiation. In considering the multitarget single-hit model, cellular sensitivity can be modified in the sense of a change in the energy per lethal event and/or in the sense of a change in the amount of ...
L, Révész, B, Littbrand
openaire   +2 more sources

Investigating the effect of radiosensitizer for Ursolic Acid and Kamolonol Acetate ‌ on HCT-116 cell line.

Bioorganic & Medicinal Chemistry, 2019
PURPOSE The aim of this study was evaluating the cytotoxic and radiosensitizing effects of Ursolic Acid (UA) and Kamolonol Acetate (KA) on HCT116 cell line and finally investigating the functional role of NF-κB and CCND1 genes in the radiosensitizing ...
Maede Hasan Abdali, S. Afshar, Abdolazim Sedighi Pashaki, D. Dastan, M. Gholami, R. Mahmoudi, M. Saidijam   +6 more
semanticscholar   +1 more source

Parameters of Radiosensitivity

Radiation Research, 1986
Dr. B. Fertil, Dr. E. P. Malaise, and co-workers have shown (1-5) that despite wide variability in the shapes of published in vitro survival curves for cells of human origin, there are, on average, systematic differences in the shapes of survival curves in the low-dose region among cells of distinct histological types.
openaire   +2 more sources

Care with radiosensitizers

The British Journal of Radiology, 1978
In current radiotherapy trials with the oxygen-mimetic radiosensitizing drugs, which are expected to overcome the potential problem of resistant hypoxic tumour cells, no allowance is being made for sensitization of normal tissue. These new agents are competing with hyperbaric oxygen (HBO) for providing therapeutic benefit, and sensitization by HBO was ...
J H, Hendry, M L, Sutton
openaire   +2 more sources

[Radiosensitizer: hypoxic cell radiosensitizer].

Gan to kagaku ryoho. Cancer & chemotherapy, 1989
There is a world-wide demand for a clinically usable sensitizer for radio-resistant hypoxic cells. After unsuccessful clinical trials of misonidazole, many efforts have been made to develop new sensitizers. In the U.S., Brown and others reported a new drug named SR-2508 (ethanidazole), which is now in phase II and III clinical trials.
openaire   +1 more source

Radiosensitization and Nanoparticles

2015
Nanomaterials have been shown to have physical and chemical properties that have opened new avenues for cancer diagnosis and therapy. Nanoconstructs that enhance existing treatments for cancer, such as radiation therapy, are being explored in several different ways. Two general paths toward nanomaterial-enabled radiosensitization have been explored: (1)
Tatjana, Paunesku, Stanley, Gutiontov, Koshonna, Brown, Gayle E, Woloschak   +3 more
openaire   +2 more sources

Care with radiosensitizers

The British Journal of Radiology, 1980
I should like to comment on the correspondence between Adams and Dische and Hendry and Sutton in The British Journal of Radiology (1979). These authors were debating the risk of sensitization of normal tissues by misonidazole at the dose levels of radiation and drug that are likely to be used clinically.
openaire   +4 more sources

Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer

Strahlentherapie und Onkologie (Print), 2021
Jenny Ling-Yu Chen, C. Pan, Yu-Li Lin, Ching‐Yi Tsai, Yu‐Sen Huang, Wen-Chi Yang, F. Hsu, S. Kuo, M. Shieh   +8 more
semanticscholar   +1 more source

PARP inhibitor niraparib as a radiosensitizer promotes antitumor immunity of radiotherapy in EGFR-mutated non-small cell lung cancer

Clinical and Translational Oncology, 2021
N. Zhang, Y. Gao, Z. Zeng, Y. Luo, X. Jiang, J. Zhang, J. Li, Y. Gong, C. Xie   +8 more
semanticscholar   +1 more source