Results 91 to 100 of about 42,443 (305)

Dosimetric and Radiobiological Comparison of Three-Dimensional Conformal Radiotherapy and Helical Tomotherapy in Whole Pelvic Radiotherapy of Prostate Cancer Patients [PDF]

Journal of Biomedical Physics and Engineering
Background: Modern radiotherapy techniques can destroy tumors with less harm to surrounding normal tissues. Normal Tissue Complication Probability (NTCP) models are useful to evaluate treatment plans.
Marziyeh Mirzaeiyan, Ali Akhavan, Alireza Amouheidari, Atoosa Adibi, Simin Hemati, Mahnaz Etehadtavakol, Hossein Khanahmad, Parvaneh Shokrani   +7 more
doaj   +1 more source

Radiation dosimetry in lung equivalent regions by use of polymer gel foams and quantitative magnetization transfer imaging [PDF]

, 2007
C
Baete, Steven, De Deene, Yves
core   +1 more source

Radiotherapy planning for glioblastoma based on a tumor growth model: Improving target volume delineation [PDF]

, 2013
Glioblastoma are known to infiltrate the brain parenchyma instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly.
Ayache, Nicholas, Dittmann, Florian, Konukoglu, Ender, Le, Matthieu, Menze, Bjoern H., Shih, Helen A., Unkelbach, Jan   +6 more
core   +5 more sources

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +12 more
wiley   +1 more source

Evaluation of Variability of Dosiomics Features with Varying Prescribed Dose in Prostate Cancer [PDF]

Journal of Biomedical Physics and Engineering
Background: Dosiomics involves converting 3D dose distribution matrices into quantifiable data for analysis. Evaluating the stability of dosiomics features against different prescribed doses is essential before utilizing them for treatment plan ...
Marziyeh Mirzaeiyan, Simin Hemati, Ali Akhavan, Mahnaz Etehadtavakol, Zahra Sharifonnasabi, Alireza mouheidari, Atoosa Adibi, Hossein Khanahmad, Parvaneh Shokrani   +8 more
doaj   +1 more source

Clinical implications of the anisotropic analytical algorithm for IMRT treatment planning and verification [PDF]

, 2008
PURPOSE: To determine the implications of the use of the Anisotropic Analytical Algorithm(AAA) for the production and dosimetric verification of IMRT plans for treatments of the prostate, parotid, nasopharynx and lung.
Al-Hallaq, Arnfield, Blanco, Bragg, Bragg, Budgell, Carrasco, Christopher M. Bragg, Eisbruch, Fogliata, Fogliata, Francescon, John Conway, Jones, Katrina Wingate, Khodri, Knoos, Mihaylov, Nelms, Partridge, Rodrigues, Sandilos, Sandilos, Shahine, Sterpin, Ulmer, Van Esch, Vanderstraeten, Van’t Riet   +28 more
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

The grid-dose-spreading algorithm for dose distribution calculation in heavy charged particle radiotherapy [PDF]

, 2007
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed.
Ahnesjö, Azusa Ishizaki, Bortfeld, Deasy, Endo, Hollmark, Hong, Kanai, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kohno, Krämer, Langen, Lomax, Mackie, Mackie, Nobuyuki Kanematsu, Noda, Petti, Russell, Schaffner, Sharpe, Shunsuke Yonai, Soukup, Szymanowski, Tsuji, Yan   +29 more
core   +3 more sources

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Evaluation of Hybrid Arc and Volumetric-Modulated Arc Therapy Treatment Plans for Fractionated Stereotactic Intracranial Radiotherapy. [PDF]

, 2018
PURPOSE: The study was aimed to compare hybrid arc and volumetric-modulated arc therapy treatment plans for fractionated stereotactic radiotherapy of brain tumors. METHODS: Treatment plans of 22 patients were studied.
Gunn, Vickie, Li, Jun, Lui, Haisong, Shi, Wenyin, To, David, Yu, Yan   +5 more
core   +1 more source