Results 91 to 100 of about 28,886 (305)

Potential advantages and pitfalls of intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) compared to 3-dimentional conformal radiotherapy (3-D CRT).

, 2013
Potential advantages and pitfalls of intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) compared to 3-dimentional conformal radiotherapy (3-D CRT).
Benjamin Slane (310995), Lexie Smith-Raymond (311001), Fabio Almeida (310991), Michelle Stevie (311003), Siyoung Jang (311005), Nam P. Nguyen (310988), Alexander Chi (310989), Dave Abraham (310999), Rick Davis (310994), Misty Ceizyk (310997), Michael Betz (310990), Vincent Vinh-Hung (10263), Steven Gelumbauskas (311007), Paul Vos (310992)   +13 more
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Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Conformal radiotherapy facilitates the delivery of concurrent chemotherapy and radiotherapy: a case of primitive neuroectodermal tumour of the chest wall.

, 2017
We illustrate the principle of conformal radiotherapy by discussing the case of a patient with a primitive neuroectodermal tumour of the chest wall. Recent advances in radiotherapy planning enable precise localization of the planning target volume (PTV ...

core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Improvements on the planning and delivery of intensity-modulated arc therapy

, 2010
In the past decade, intensity-modulated radiation therapy (IMRT) has taken a significant step towards dose conformality and has now become a standard radiotherapy technique in the clinic.
Tang, G.
core  

Hormonal therapy and 3D conformal radiotherapy in prostate cancer: early toxicity of combined treatment

, 2001
PurposeTo evaluate acute toxicity of combined treatment (androgen ablation and high-dose 3D conformal radiotherapy [3D-CRT]) in patients with a localized cancer of prostate.Materials and methodsBetween April 1999 and March 2000, at the Greatpoland Cancer
Milecki, Piotr; Department of Radiotherapy, Greatpoland Cancer Centre, ul. Garbary 15, 61-866 Poznań, Poland, Stryczyńska, Grażyna; Department of Radiotherapy, Greatpoland Cancer Centre, ul. Garbary 15, 61-866 Poznań, Poland, Stachowski, Tomasz; Chair of Urology, University School of Medical Sciences, ul. Kurlandzka 1, 61-650 Poznań, Poland, Kwias, Zbigniew; Chair of Urology, University School of Medical Sciences, ul. Kurlandzka 1, 61-650 Poznań, Poland, Nawrocki, Sergiusz; Department of Radiotherapy, Greatpoland Cancer Centre, ul. Garbary 15, 61-866 Poznań, Poland   +4 more
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Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Literature-based recommendations for treatment planning and execution in high-dose radiotherapy for lung cancer.

, 2004
BACKGROUND AND PURPOSE: To review the literature on techniques used in high-dose radiotherapy of lung cancer in order to develop recommendations for clinical practice and for use in research protocols.
Mirimanoff, R, Senan, S., Senan, S., Budach, V, Giraud, Philippe, De Ruysscher, D., Mirimanoff, R., Senan, Suresh, Mirimanoff, René, Budach, Volker, Giraud, P., Ruysscher, D De, Giraud, P, De Ruysscher, Dirk, Budach, V.   +14 more
core   +1 more source

An Italian survey on “palliative intent” radiotherapy

, 2022
Background: The aim of this paper is to provide a comprehensive overview of the scenario on radiotherapy (RT) delivered with palliative intent in Italy.
Parisi S., Santacaterina A., Cacciola A., Cellini F., Arcidiacono F., Tamburella C., Pergolizzi S., Ferini G., Draghini L., Trippa F., Lillo S., Maranzano E.   +11 more
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Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source