Results 71 to 80 of about 28,886 (305)

Adjuvant Radiotherapy with Three-Dimensional Conformal Radiotherapy of Lacrimal Gland Adenoid Cystic Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background & Aim: Adenoid cystic carcinoma (ACC) of lacrimal gland is a rare tumour with aggressive behaviour. There is sparse data to address optimum therapy for such tumours.
Vikas Roshan, Sushmita Pathy, Supriya Mallick, Subhash Chander, Seema Sen, Bhavna Chawla   +5 more
doaj   +1 more source

Conformal radiotherapy of prostate carcinoma: Procedure description

, 2011
Introduction. Today, three-dimensional conformal radiotherapy is a standard way in the radical treatment of localized prostate cancer, and it is an alternative to the radical prostatectomy.
Dusanka Tesanovic, Dragan Arandjelovic, Ilinka Nadj, Marko Erak, Dragica Erak, Biljana Bugarcic   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients

, 2013
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Markus Ratka, Milickovic, Natasa, Nikolaos Zamboglou, Dimos Baltas, Zamboglou, Nikolaos, Ratka, Markus, Natasa Milickovic, Chatzikonstantinou, Georgios, Tunn, Ulf W., Baltas, Dimos, Tselis, Nikolaos, Georgios Chatzikonstantinou, Nikolaos Tselis, Ulf W Tunn   +13 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dosimetric and Radiobiological Comparison of Three-Dimensional Conformal Radiotherapy and Helical Tomotherapy in Whole Pelvic Radiotherapy of Prostate Cancer Patients [PDF]

Journal of Biomedical Physics and Engineering
Background: Modern radiotherapy techniques can destroy tumors with less harm to surrounding normal tissues. Normal Tissue Complication Probability (NTCP) models are useful to evaluate treatment plans.
Marziyeh Mirzaeiyan, Ali Akhavan, Alireza Amouheidari, Atoosa Adibi, Simin Hemati, Mahnaz Etehadtavakol, Hossein Khanahmad, Parvaneh Shokrani   +7 more
doaj   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

Advanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele, Hossein Ipakchi, Tizazu H. Mekonnen   +2 more
wiley   +1 more source

Evaluation of Variability of Dosiomics Features with Varying Prescribed Dose in Prostate Cancer [PDF]

Journal of Biomedical Physics and Engineering
Background: Dosiomics involves converting 3D dose distribution matrices into quantifiable data for analysis. Evaluating the stability of dosiomics features against different prescribed doses is essential before utilizing them for treatment plan ...
Marziyeh Mirzaeiyan, Simin Hemati, Ali Akhavan, Mahnaz Etehadtavakol, Zahra Sharifonnasabi, Alireza mouheidari, Atoosa Adibi, Hossein Khanahmad, Parvaneh Shokrani   +8 more
doaj   +1 more source

Recent Advances İn Radiotherapy

, 2012
Recent advances in computer technology have parallel advances in imaging techniques.. The improvements in imaging have in turn allowed a higher level of complexity in radiotherapy treatment planning systems.
Serap Akyürek
core   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source