Results 51 to 60 of about 300,304 (238)

Conformational radiotherapy of no metastatic prostate cancer: Experience of the radiation therapy department of EHS Oncology Emir Abdelkader of Oran

Journal de la Faculté de Médecine d'Oran, 2022
Introduction - Over the last decades, prostate cancer has become a public health condition, due to its frequency and severity. The conformational radiotherapy constituted today the standard technique in the irradiation of non-metastatic prostate cancers
Lotfi TALEB, Karima CHENNI, Ismail Zergoug, Abdelbaki Boukerche, Ahmed Fethi Dali-Youcef   +4 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Concurrent Hypofractionated Three-dimensional Re-irradiation and Temozolomide in Recurrent Malignant Glioma

Middle East Journal of Cancer, 2012
Background: This study determines the efficacy and tolerability of hypofractionated three-dimensional conformal radiotherapy in conjunction with daily temozolomide in treatment of previously irradiated recurrent malignant glioma.Methods: We enrolled 21 ...
Doaa Ali Sharaf Eldeen, Eman Abd Elkareem Toson, Maiy Abd Elraheem Alshahat, Ahmed Nageeb Taha   +3 more
doaj  

Salvage conformal radiotherapy for biochemical recurrent prostate cancer after radical prostatectomy

International Brazilian Journal of Urology, 2006
OBJECTIVE: Assess the results of salvage conformal radiotherapy in patients with biochemical failure after radical prostatectomy and identify prognostic factors for biochemical recurrence and toxicity of the treatment.
Carlos R. Monti, Ricardo A. Nakamura, Robson Ferrigno, Aristides Rossi Jr, Neusa S. Kawakami, Felipe A. Trevisan   +5 more
doaj   +1 more source

Ovarian Transposition Strategy in Patients with Cervical Cancer Who Undergo Pelvic Radiation: Proposal of Ovarian Placement Based on Virtual Simulations

European Medical Journal Innovations, 2021
Objective: To establish a proposal for the location for ovarian transposition, considering different irradiation techniques and time to ovarian failure.
Gabriel Oliveira Bernardes Gil, Cassiano Asano, Maria Luísa Braga Vieira Gil, Warne Andrade, Eduardo Batista Cândido, Marcos Regalin, Izabella Nobre Queiroz, Darly Gomes Soares Delfino, Farley Soares Cantídio, Agnaldo Lopes Silva-Filho   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Three-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma in Patients Unfit for Resection, Ablation, or Chemotherapy: A Retrospective Study

The Scientific World Journal, 2013
Purpose. The purpose is to evaluate the feasibility, efficacy, and the toxicity of three-dimensional conformal radiotherapy (3DCRT) in patients with advanced hepatocelluar carcinoma (HCC) and inferior vena cava tumor thrombosis (IVCTT). Methods.
Vassilis Kouloulias, Eftychia Mosa, John Georgakopoulos, Kalliopi Platoni, Ilias Brountzos, Anna Zygogianni, Christos Antypas, Paraskevas Kosmidis, Kyriaki Mystakidou, Maria Tolia, Ivelina Beli, Athanasios Gouliamos, John Kouvaris, Nikoalos Kelekis   +13 more
doaj   +1 more source

Three-dimensional conformal radiotherapy versus intensity-modulated radiotherapy in carcinoma cervix

Journal of Clinical and Scientific Research, 2018
Background: Cervical cancer is the most common gynecological cancer among Indian women. 3D-CRT treatment is associated with more acute and late toxicities, because of close proximity of bladder and rectum to the cervix.
Revathi Badiginchala, Swapna Jilla, B V Subramanian, Prana Bandhu Das, Archana Prathipati, G Sanjeeva Kumar   +5 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy

Radiation Oncology, 2008
Background The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes.
Korevaar Erik W, Maduro John H, Dolsma Wil V, van der Laan Hans, Langendijk Johannes A   +4 more
doaj   +1 more source