Results 51 to 60 of about 28,886 (305)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Concurrent Hypofractionated Three-dimensional Re-irradiation and Temozolomide in Recurrent Malignant Glioma

Middle East Journal of Cancer, 2012
Background: This study determines the efficacy and tolerability of hypofractionated three-dimensional conformal radiotherapy in conjunction with daily temozolomide in treatment of previously irradiated recurrent malignant glioma.Methods: We enrolled 21 ...
Doaa Ali Sharaf Eldeen, Eman Abd Elkareem Toson, Maiy Abd Elraheem Alshahat, Ahmed Nageeb Taha   +3 more
doaj  

Three-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma in Patients Unfit for Resection, Ablation, or Chemotherapy: A Retrospective Study

The Scientific World Journal, 2013
Purpose. The purpose is to evaluate the feasibility, efficacy, and the toxicity of three-dimensional conformal radiotherapy (3DCRT) in patients with advanced hepatocelluar carcinoma (HCC) and inferior vena cava tumor thrombosis (IVCTT). Methods.
Vassilis Kouloulias, Eftychia Mosa, John Georgakopoulos, Kalliopi Platoni, Ilias Brountzos, Anna Zygogianni, Christos Antypas, Paraskevas Kosmidis, Kyriaki Mystakidou, Maria Tolia, Ivelina Beli, Athanasios Gouliamos, John Kouvaris, Nikoalos Kelekis   +13 more
doaj   +1 more source

Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy

Radiation Oncology, 2008
Background The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes.
Korevaar Erik W, Maduro John H, Dolsma Wil V, van der Laan Hans, Langendijk Johannes A   +4 more
doaj   +1 more source

A prospective, comparative analysis of acute toxicity profile between three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) in locally advanced head and neck cancer patients

Cancer Treatment and Research Communications, 2020
Introduction: The advances of modern radiotherapy have emerged with the development of conformal radiotherapy techniques, such as the three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT).
Nilesh Kucha, Tej Prakash Soni, Naresh Jakhotia, Nidhi Patni, Dinesh Kumar Singh, Anil Kumar Gupta, Lalit Mohan Sharma, Jaishree Goyal   +7 more
doaj   +1 more source

Point Dose Measurement for Verification of Treatment Planning System using an Indigenous Heterogeneous Pelvis Phantom for Clarkson, Convolution, Superposition, and Fast Superposition Algorithms [PDF]

Journal of Biomedical Physics and Engineering, 2019
Background: Nowadays, advanced radiotherapy equipment includes algorithms to calculate dose. The verification of the calculated doses is important to achieve accurate results. Mostly homogeneous dosimetric phantoms are available commercially which do not
S Singh, P Raina, O P Gurjar
doaj   +1 more source

Toxicity and outcome of intensity-modulated radiotherapy versus 3-dimensional conformal radiotherapy for oropharyngeal cancer: A matched-pair analysis

, 2013
Because of the scarcity of randomized trials comparing toxicity and outcomes of intensity-modulated radiotherapy (IMRT) for oropharyngeal cancer (OPC) with 3D-conformal radiotherapy (3DCRT), we performed a matched-pair analysis from prospectively ...
Tans, Lisa, Tans, L. (Lisa), Teguh, D.N. (David), Rooij, P.H. (Peter) van, Teguh, DN, Al-Mamgani, Abrahim, Levendag, P.C. (Peter), Levendag, Peter, Al-Mamgani, A. (Abrahim), Rooij, Peter   +9 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Three-dimensional conformal radiotherapy versus intensity-modulated radiotherapy in carcinoma cervix

Journal of Clinical and Scientific Research, 2018
Background: Cervical cancer is the most common gynecological cancer among Indian women. 3D-CRT treatment is associated with more acute and late toxicities, because of close proximity of bladder and rectum to the cervix.
Revathi Badiginchala, Swapna Jilla, B V Subramanian, Prana Bandhu Das, Archana Prathipati, G Sanjeeva Kumar   +5 more
doaj   +1 more source

Treatment of primary liver cancer using highly-conformal radiotherapy with kv-image guidance and respiratory control

, 2012
Purpose: To implement a reliable, practical and reproducible treatment procedure, based on in-room kV-image guidance and respiratory control, for liver cancer patients treated with high dose conformal radiotherapy using a commercially available treatment
Lao, Wai Cheung, Michael C.H. Lee, Anne W.M. Lee, Ng, Wai Tong, Wai-Cheung Lao, Kai-Hung Fung, Wai-Tong Ng, Francis Li, Augustine T.S. Chan, Li, Francis, Lee, Michael C H, Chan, Augustine T S, Lee, Anne W M, Ada L.Y. Law, Fung, Kai Hung, Law, Ada L Y   +15 more
core   +1 more source