Results 41 to 50 of about 28,886 (305)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
PET/CT fusion in radiotherapy planning for lung cancer - case reports [PDF]
Vojnosanitetski Pregled, 2016 Introduction. Application of imaging methods, namely computed tomography (CT), magnetic resonance imaging (MRI) and in recent years positron emission tomography-computed tomography (PET/CT), and the progress of computer technology have allowed ...
Erak Marko Đ. +4 more
doaj +1 more source
Conformal radiotherapy for prostate cancer
Annals of Medicine, 2000 This review presents the contribution conformal treatment has made to the external beam treatment of prostate cancer drawing on 10 years of experience with three-dimensional conformal radiation treatment in 1500 patients with prostate cancer at our institution.
openaire +2 more sources
Journal de la Faculté de Médecine d'Oran, 2022 Introduction - Over the last decades, prostate cancer has become a public health condition, due to its frequency and severity. The conformational radiotherapy constituted today the standard technique in the irradiation of non-metastatic prostate cancers
Lotfi TALEB +4 more
doaj
European Medical Journal Innovations, 2021 Objective: To establish a proposal for the location for ovarian transposition, considering different irradiation techniques and time to ovarian failure.
Gabriel Oliveira Bernardes Gil +9 more
doaj +1 more source
Quantification of geometric uncertainties in image guided radiotherapy [PDF]
, 2010 The aim of this thesis is to determine if the geometric uncertainties that are introduced into the image guided radiotherapy (IGRT) process by Cone Beam CT (CBCT) based IGRT equipment are sufficiently small that they do not pose a significant risk of ...
Sykes, Jonathan
core
, 2008 Since 1982, the Radiation Oncology Group of the EORTC (EORTC ROG) has pursued an extensive Quality Assurance (QA) program involving all centres actively participating in its clinical research.
Collette, L. +23 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Salvage conformal radiotherapy for biochemical recurrent prostate cancer after radical prostatectomy
International Brazilian Journal of Urology, 2006 OBJECTIVE: Assess the results of salvage conformal radiotherapy in patients with biochemical failure after radical prostatectomy and identify prognostic factors for biochemical recurrence and toxicity of the treatment.
Carlos R. Monti +5 more
doaj +1 more source