Results 131 to 140 of about 300,304 (238)

Effects of Biotin on a Fluorescein‐Based Photosensitizer Revealed by Multiscale Computational Modeling

Chemistry – A European Journal, EarlyView.
Biotinylation of a fluorescein‐based photosensitizer enhances its performance in PDT through a synergistic dual action. In addition to Type II singlet oxygen generation common to both dyes, the biotinylated system induces stronger membrane perturbation and higher local accumulation in lipid membranes, associated with increased water permeability and ...
Valeria Butera, Alessandra Gilda Ritacca, Giampaolo Barone, Nino Russo, Marta Erminia Alberto   +4 more
wiley   +1 more source

Conformal radiotherapy (3-DCRT)

, 2009
U radu su prikazana osnovna načela i postupci važni za provođenje konformalne radioterapije. Radi se o specifičnoj radioterapijskoj metodi koja se sastoji od dva sistema: jedan čine CT-simulator i računalo, a drugi služi za samo provođenje radioterapije.
Deponte, Vlado
core   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana, Ernest Musekwa, Erica‐Mari Nell, Zivanai Cuthbert Chapanduka   +3 more
wiley   +1 more source

Sustainable plant‐leaf‐derived carbon dots with deep‐red emission enable 1‐min photodynamic therapy of tumors

FlexMat, EarlyView.
In this study, plant‐derived carbon dots (CDs) were prepared using natural plant leaves as raw materials through solvothermal method. These CDs retain the porphyrin structure from chlorophyll and can simultaneously generate I and II types of reactive oxygen species. A 660 nm laser irradiation for only 1 min can achieve efficient photodynamic anti‐tumor
Renjing Chen, Danjie Han, Zemin Wang, Xinyi Lu, Peng He, Lili Hou, Chuantong Cheng, Xueting Liu, Jinli Liu, Zhiming Wang, Zongwen Liu, Xingtao Zhou, Zichao Luo, Kebin Lin   +13 more
wiley   +1 more source

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

Pattern of Failure in Nasopharyngeal Carcinoma After Radiotherapy in a Low‐Incidence Population: A DAHANCA Study

Head &Neck, EarlyView.
ABSTRACT Background Nasopharyngeal carcinoma (NPC) is uncommon in many populations. Most existing clinical evidence comes from endemic areas, where Epstein–Barr virus (EBV)‐associated subtypes predominate. We analyzed patterns of failure in a population‐based cohort from Denmark, a low‐incidence setting.
Anne Marie Lindegaard, Katrin Haakansson, Maria Andersen, Mogens Bernsdorf, Jesper G. Eriksen, Mohammad Farhadi, Lisa L. Hjalgrim, Kenneth Jensen, Giedrius Lelkaitis, Christian Maare, Jens Overgaard, Christina Caroline Plaschke, Erik Schiess, Ruta Zukuskaite, Jeppe Friborg   +14 more
wiley   +1 more source

Conditional sparing in FLASH radiotherapy: Conformal dosimetry and ALARA remain essential. [PDF]

J Appl Clin Med Phys
Chang CC, Ma Y, Kang M, Paliwal B, Morris Z, Durkee B, Cheng C.   +6 more
europepmc   +1 more source

A Comparative Study of the Acute Toxicities of Three-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity-Modulated Radiotherapy (IMRT) in Locally Advanced and Inoperable Oral Cavity Cancer. [PDF]

Cureus
Rahamat Ullah M, Sarkar UK, Hoque SMA, Sarker NK.   +3 more
europepmc   +1 more source