Results 141 to 150 of about 42,043 (282)

Disparities in Proton Radiation Utilization for HPV‐Associated Oropharyngeal Cancer Following TORS

Head &Neck, EarlyView.
ABSTRACT Introduction Racial, socioeconomic, and geographic disparities in receipt of proton radiation have been reported. Whether disparities exist for oropharyngeal squamous cell carcinoma (OPSCC) is not well studied. Methods Patients with HPV‐associated OPSCC treated with transoral robotic surgery (TORS) and adjuvant radiation from 2016 to 2023 were
Jane Y. Tong, Vera Bzhilyanskaya, Jason K. Molitoris, Matthew J. Ferris, Kyle M. Hatten   +4 more
wiley   +1 more source

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

International Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea, Pierre Loap, Sofiane Allali, Alain Fourquet, Kim Cao, Youlia Kirova   +5 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Managing stage IV thymic carcinoma-a narrative review of radiation therapy strategies and options. [PDF]

Mediastinum
Shepherd AF.
europepmc   +1 more source

Comparison of Auto‐Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy

Journal of Medical Radiation Sciences, EarlyView.
Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial‐spinal radiation therapy (CSI) is a time‐consuming, labour‐intensive task. This study aims to assess the accuracy and clinical acceptability of auto‐contours produced by the Siemens DirectORGANS auto‐contouring software on paediatric patients receiving CSI treatment ...
Isabel Cant, Jonathan Sykes, Yolanda Surjan, Rachael Beldham‐Collins, Laura Murphy, John Fernandez, Alison Salkeld   +6 more
wiley   +1 more source

Multimodal, Personalized Treatment of Pineal Region Tumors in Adulthood-A Single Center Study. [PDF]

J Clin Med
Mezei T, Báskay J, Pollner P, Németh L, Markia B, Nagy G, Bajcsay A, Sipos L.   +7 more
europepmc   +1 more source

miR‐127‐3p Inhibits Cell Stemness and Docetaxel Resistance in Triple‐Negative Breast Cancer by Targeting KIF3B

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the mechanism of miR‐127‐3p in tumor cell stemness and docetaxel (DTX) resistance in triple‐negative breast cancer (TNBC). hsa‐miR‐127‐3p and KIF3B levels were predicted using databases and validated in TNBC and paracancerous tissues.
Zi‐Chao He, Jun‐Jie Zhao, Ting Yan
wiley   +1 more source

Optimizing radiation dose and fractionation for the definitive treatment of locally advanced non-small cell lung cancer [PDF]

, 2018
Bradley, Jeffrey D, Roach, Michael C, Robinson, Cliff G   +2 more
core   +1 more source