Results 11 to 20 of about 1,908,615 (320)

Preclinical tumor control with a laser-accelerated high-energy electron radiotherapy prototype

open access: yesNature Communications, 2023
Radiotherapy using very-high-energy electron (VHEE) beams (50-300 MeV) has attracted considerable attention due to its advantageous dose deposition characteristics, enabling deep penetration and easy manipulation by magnetic components.
Zhiyuan Guo   +11 more
doaj   +2 more sources

Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators

open access: yesFrontiers in Physics, 2020
We have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors.
Karolina Kokurewicz   +9 more
doaj   +2 more sources

CERN-based experiments and Monte-Carlo studies on focused dose delivery with very high energy electron (VHEE) beams for radiotherapy applications

open access: yesScientific Reports
Very High Energy Electron (VHEE) beams are a promising alternative to conventional radiotherapy due to their highly penetrating nature and their applicability as a modality for FLASH (ultra-high dose-rate) radiotherapy. The dose distributions due to VHEE
L. Whitmore   +7 more
doaj   +2 more sources

MOSkin dosimetry for an ultra-high dose-rate, very high-energy electron irradiation environment at PEER

open access: yesFrontiers in Physics
FLASH radiotherapy, which refers to the delivery of radiation at ultra-high dose-rates (UHDRs), has been demonstrated with various forms of radiation and is the subject of intense research and development recently, including the use of very high-energy ...
James Cayley   +6 more
doaj   +2 more sources

Clinical application of high‐LET radiotherapy combined with immunotherapy in malignant tumors

open access: yesPrecision Radiation Oncology
The superior physical and biological properties of high linear energy transfer (LET), as opposed to traditional low‐LET rays, underscore the advantage of proton therapy (PRT) and carbon ion radiotherapy (CIRT) are better than traditional photon ...
Kexin Meng, Haijun Lu
doaj   +2 more sources

Tomographic detection of photon pairs produced from high-energy X-rays for the monitoring of radiotherapy dosing

open access: yesNature Biomedical Engineering, 2022
Measuring the radiation dose reaching a patient’s body is difficult. Here we report a technique for the tomographic reconstruction of the location of photon pairs originating from the annihilation of positron–electron pairs produced by high-energy X-rays
Q. Lyu, R. Neph, K. Sheng
semanticscholar   +1 more source

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

open access: yes, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R.   +3 more
core   +3 more sources

Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients [PDF]

open access: yes, 2020
Background: A Phase III randomized controlled trial investigating the addition of modulated electro-hyperthermia (mEHT) to chemoradiotherapy for locally advanced cervical cancer patients is being conducted in South Africa (Human Research Ethics Committee
Ayeni, Olusegun   +4 more
core   +2 more sources

Toward an effective use of laser-driven very high energy electrons for radiotherapy: Feasibility assessment of multi-field and intensity modulation irradiation schemes

open access: yesScientific Reports, 2020
Radiotherapy with very high energy electrons has been investigated for a couple of decades as an effective approach to improve dose distribution compared to conventional photon-based radiotherapy, with the recent intriguing potential of high dose-rate ...
L. Labate   +13 more
semanticscholar   +1 more source

Overview of the sensitivity of Ge- and Al-doped silicon dioxide optical fibres to ionizing radiation [PDF]

open access: yes, 2012
This paper reviews the thermoluminescence sensitivity of Ge- and Al- doped SiO2 optical fibre subjected to various ionizing radiations. It is found that the Ge- doped SiO2 optical fiber has the thermoluminescence response superior to Al-doped SiO2 ...
Hashim, Suhairul   +3 more
core   +1 more source

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