Results 201 to 210 of about 156,533 (274)

Initial follow-up of mechanical QC tests for RapidArc Dynamic (RAD). [PDF]

J Appl Clin Med Phys
Van Riet E, Piot W, Vanstraelen B, Aerts K, Reynders T, Depuydt T, Crijns W.   +6 more
europepmc   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

Validation of the 8th Edition of the UICC/AJCC Staging System for Nasopharyngeal Carcinoma From Endemic Areas in the Intensity-Modulated Radiotherapy Era.

The Journal of the National Comprehensive Cancer Network, 2017
Ling-Long Tang, Yupei Chen, Y. Mao, Zixian Wang, R. Guo, Lei Chen, L. Tian, A. Lin, Li Li, Ying Sun, Jun Ma   +10 more
semanticscholar   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Radiotherapy commissioning and tariff-how can we deliver advanced, innovative, and personalised radiotherapy? [PDF]

Br J Radiol
Powell Brown I, Hutton D, Thorp N, Thomson J, MacKay R, Hacker L, Ashmore L, Hayes J, Archer J, Rowbottom C.   +9 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Assessment and Comparison of 3D Conformal Radiotherapy With Volumetric Modulated Arc Therapy for Preserving Remaining Brain Volume in High-Grade Gliomas. [PDF]

Cureus
Singh HB, Mani N, Singh P, Jaiswal A, Chauhan S, Mishra M.   +5 more
europepmc   +1 more source

Osteoradionecrosis of the mandible in patients with oropharyngeal carcinoma treated with intensity‐modulated radiotherapy

Cancer, 2017
F. Caparrotti, S. Huang, Lin Lu, S. Bratman, J. Ringash, A. Bayley, John Cho, M. Giuliani, John J. Kim, J. Waldron, A. Hansen, L. Tong, Wei Xu, B. O'Sullivan, R. Wood, D. Goldstein, A. Hope   +16 more
semanticscholar   +1 more source

In Situ Synthesis of a Tumor Microenvironment‐Activated Radiosensitizing Cu2‐xS/LDH Probe for Photoacoustic Imaging‐Guided Radiotherapy

Advanced Science, EarlyView.
We reported a new kind of organic‐inorganic composite nanomaterial with excellent PA imaging performance after the in situ activation by hydrogen sulfide in colorectal cancer tissues, which was used for precise radiotherapy of colorectal cancer. It shows a great application potential for early diagnosis and treatment of tumor.
Kang Zhu, Qiaoqiao Wei, Ying Wu, Qingqing Li, Luntao Liu, Chunxiang Mo, Chuqiao Liu, Lichao Su, Jibin Song   +8 more
wiley   +1 more source

Risk factors for early-onset radiodermatitis in patients with locally advanced breast cancer: a comparative analysis of volumetric modulated arc therapy and intensity-modulated radiotherapy. [PDF]

Breast Cancer
Chang CC, Huang PW, Lin JC, Tsai JT, Hsu SM.   +4 more
europepmc   +1 more source