Results 11 to 20 of about 1,390,389 (383)
Nature Reviews Disease Primers, 2019 Radiotherapy is used in >50% of patients with cancer, both for curative and palliative purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal tissue can also be damaged, leading to toxicity. Modern and precise radiotherapy techniques, such as intensity-modulated radiotherapy, may prevent toxicity, but some patients ...
D. de Ruysscher +5 more
semanticscholar +6 more sources
Adaptive radiotherapy: The Elekta Unity MR-linac concept
Clinical and Translational Radiation Oncology, 2019 Background and purpose: The promise of the MR-linac is that one can visualize all anatomical changes during the course of radiotherapy and hence adapt the treatment plan in order to always have the optimal treatment.
Dennis Winkel +17 more
doaj +2 more sources
Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.
New England Journal of Medicine, 2023 Background Robust data on patient-reported outcome measures comparing treatments for clinically localized prostate cancer are lacking. We investigated the effects of active monitoring, radical prostatectomy, and radical radiotherapy with hormones on ...
semanticscholar +1 more source
Molecular mechanisms of tumor resistance to radiotherapy
Molecular Cancer, 2023 Background Cancer is the most prevalent cause of death globally, and radiotherapy is considered the standard of care for most solid tumors, including lung, breast, esophageal, and colorectal cancers and glioblastoma.
Yuehua Wu +3 more
semanticscholar +1 more source
Journal of Clinical Oncology, 2022 PURPOSE To ascertain if preoperative short-term radiotherapy followed by chemotherapy is not inferior to a standard schedule of long-term chemoradiotherapy in patients with locally advanced rectal cancer.
J. Jin +34 more
semanticscholar +1 more source
Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Signal Transduction and Targeted Therapy, 2022 Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic effect on remote and non-irradiated tumor deposits, which is called abscopal effect.
Zengfu Zhang +3 more
semanticscholar +1 more source
JAMA Oncology, 2022 Importance To our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use of proton FLASH.
A. Mascia +17 more
semanticscholar +1 more source
Ferroptosis, radiotherapy, and combination therapeutic strategies
Protein & Cell, 2021 Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently been revealed to play an important role in radiotherapy-induced cell ...
Guang Lei +4 more
semanticscholar +1 more source
MedComm, 2021 Cancer is a leading cause of death worldwide. Surgery is the primary treatment approach for cancer, but the survival rate is very low due to the rapid progression of the disease and presence of local and distant metastasis at diagnosis.
Ya-Ping Liu +5 more
semanticscholar +1 more source