Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-a randomised trial [PDF]
, 2014 Background: The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer.
Holtveg, Helle M R +39 more
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Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based study. [PDF]
, 2007 BACKGROUND: Breast radiotherapy as practised in the 1970s and 1980s resulted in significant myocardial exposure, and this was higher when the left breast was treated.
Putcha, V +18 more
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Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]
, 2008 <p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A. +9 more
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Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
Cancer Discovery, 2021 Low-dose radiotherapy triggered T-cell infiltration into poorly inflamed tumors and reprogrammed both the adaptive and innate immune landscape to allow responsiveness to combinatorial immunotherapy.
F. Herrera +38 more
semanticscholar +1 more source
Stem Cells International, 2022 The radiation resistance of cancer stem cells poses a critical obstacle for management of non-small-cell lung cancer (NSCLC). It is interesting to note that E3 ubiquitin ligase CHIP is involved in radiation resistance and stemness phenotypes in NSCLC ...
Bo Tan +4 more
doaj +1 more source
Letter. Intensity-modulated radiotherapy for the treatment of breast cancer [PDF]
, 2013 In the systematic review of intensity-modulated radiotherapy (IMRT) in the treatment of breast cancer reported in Clinical Oncology by Dayes and colleagues [1], the only prospective randomised clinical trial (n = 306) testing forward-planned IMRT to have
Haviland, J.S. +3 more
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Journal of Immunology Research, 2022 Breast cancer (BC) is the most commonly diagnosed cancer and second leading cause of cancer-related death in women worldwide. Ferroptosis, an iron-dependent newly discovered mode of cell death, can be induced by lenaltinib and plays an important role in ...
Jiahao Zhu +6 more
doaj +1 more source
Technology-driven research for radiotherapy innovation [PDF]
, 2020 Technology has a pivotal role in the continuous development of radiotherapy. The long road toward modern 'high-tech' radiation oncology has been studded with discoveries and technological innovations that resulted from the interaction of various ...
Heijmen, B.J.M. (Ben) +16 more
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DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
Signal Transduction and Targeted Therapy, 2020 Radiotherapy is one of the most common countermeasures for treating a wide range of tumors. However, the radioresistance of cancer cells is still a major limitation for radiotherapy applications.
Rui-Xue Huang, P. Zhou
semanticscholar +1 more source
Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): A feasibility study [PDF]
, 2006 Background: Concurrent chemoradiotherapy has improved survival in inoperable stage III non-small cell lung cancer (NSCLC). This phase I trial was performed in order to establish a dose recommendation for oral vinorelbine in combination with cisplatin and
Schmidt, Michael +8 more
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