Results 21 to 30 of about 510,570 (268)

Radiotherapy for meningiomas

Journal of Neuro-Oncology, 2022
AbstractMeningiomas are the most common primary central nervous system neoplasm. Despite promising recent progress in elucidating the genomic landscape and underlying biology of these histologically, molecularly, and clinically diverse tumors, the mainstays of meningioma treatment remain maximal safe resection and radiation therapy.
Chen, William C, Perlow, Haley K, Choudhury, Abrar, Nguyen, Minh P, Mirchia, Kanish, Youngblood, Mark W, Lucas, Calixto-Hope G, Palmer, Joshua D, Magill, Stephen T, Raleigh, David R   +9 more
openaire   +4 more sources

E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells

Stem Cells International, 2022
The radiation resistance of cancer stem cells poses a critical obstacle for management of non-small-cell lung cancer (NSCLC). It is interesting to note that E3 ubiquitin ligase CHIP is involved in radiation resistance and stemness phenotypes in NSCLC ...
Bo Tan, Jingwei Zhang, Wen Wang, Haibo Ma, Yuanyuan Yang   +4 more
doaj   +1 more source

Correlation between Ferroptosis-Related Gene Signature and Immune Landscape, Prognosis in Breast Cancer

Journal of Immunology Research, 2022
Breast cancer (BC) is the most commonly diagnosed cancer and second leading cause of cancer-related death in women worldwide. Ferroptosis, an iron-dependent newly discovered mode of cell death, can be induced by lenaltinib and plays an important role in ...
Jiahao Zhu, Qingqing Chen, Ke Gu, You Meng, Shengjun Ji, Yutian Zhao, Bo Yang   +6 more
doaj   +1 more source

Role of chemotherapy in nasopharyngeal carcinoma

Oncology Reviews, 2012
Nasopharyngeal carcinoma (NPC) is a unique malignant head and neck cancer with clinical, demographic, and geographic features distinct from other head and neck epithelial malignancies.
Fabiola Paiar, Vanessa Di Cataldo, Giacomo Zei, Eleonora Monteleone Pasquetti, Sara Cecchini, Icro Meattini, Monica Mangoni, Benedetta Agresti, Carmine Iermano, Pierluigi Bonomo, Giampaolo Biti   +10 more
doaj   +1 more source

Radiotherapy Dose and Induction Chemotherapy Cycles Are Associated With Prognosis and Toxicity Risk: A Retrospective Study of 227 Patients With Unresectable Stage III Non-Small-Cell Lung Cancer

Technology in Cancer Research & Treatment, 2020
Objective: Concurrent chemoradiation (cCHRT) has been confirmed as the standard treatment for local advanced non-small-cell lung cancer (NSCLC). This study is to assess the appropriate timing of radiotherapy and cycles of induction chemotherapy for those
Liyao Chen, Yu Hou, Yaoxiong Xia, Li Chang, Xianmin Diao, Li Wang, Lan Li, Qing Long, Ying Liu, Yan Liu, Wenhui Li   +10 more
doaj   +1 more source

Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors

Radiation Oncology, 2022
Background To analyze RapidPlan knowledge-based models for DVH estimation of organs at risk from breast cancer VMAT plans presenting arc sectors en-face to the breast with zero dose rate, feature imposed during the optimization phase (avoidance sectors ...
Antonella Fogliata, Sara Parabicoli, Lucia Paganini, Giacomo Reggiori, Francesca Lobefalo, Luca Cozzi, Ciro Franzese, Davide Franceschini, Ruggero Spoto, Marta Scorsetti   +9 more
doaj   +1 more source

ALDH1A3–Linc00284 Axis Mediates the Invasion of Colorectal Cancer by Targeting TGFβ Signaling via Sponging miR-361-5p

International Journal of Genomics, 2022
ALDH1A3 and Linc00284 involve in colorectal cancer (CRC) development; however, the regulatory mechanism is still unclear. In this study, we collected clinicopathological characteristics and tissue samples from 73 CRC patients to analyze the expression of
Chunlin Ke, Minmin Shen, Peirong Wang, Zhihua Chen, Suyong Lin, Feng Dong   +5 more
doaj   +1 more source

Risk factors for radiation-induced lung injury in patients with advanced non-small cell lung cancer: implication for treatment strategies

World Journal of Surgical Oncology, 2021
Background The radiation-induced lung injury (RILI) in patients with advanced non-small cell lung cancer (NSCLS) is very common in clinical settings; we aimed to evaluate the risk factors of RILI in NSCLS patients, to provide insights into the treatment ...
Sha Sha, Jigang Dong, Maoyu Wang, Ziyu Chen, Peng Gao   +4 more
doaj   +1 more source

Antiangiogenics and radiotherapy

Journal of Pharmacy and Pharmacology, 2008
Abstract Antiangiogenic therapies are one of the fore-runners of the new generation of anticancer drugs aimed at tumour-specific molecular targets. Up until the beginning of this century, the general opinion was that targeted agents should show antitumour activity when used as single agents.
Shannon, Aoife M., Williams, Kaye J.
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source