Results 11 to 20 of about 1,093,427 (365)
Adaptive Radiotherapy: Next-Generation Radiotherapy
CancersSimple Summary Radiotherapy, a crucial cancer treatment, has evolved significantly over the years. Traditionally, treatment plans were based on initial scans used throughout the treatment course, accounting for changes in the patient’s anatomy by ...
O. Dona Lemus +4 more
semanticscholar +5 more sources
Adaptive radiotherapy: The Elekta Unity MR-linac concept
Clinical and Translational Radiation Oncology, 2019 Background and purpose: The promise of the MR-linac is that one can visualize all anatomical changes during the course of radiotherapy and hence adapt the treatment plan in order to always have the optimal treatment.
Dennis Winkel +17 more
doaj +2 more sources
Molecular mechanisms of tumor resistance to radiotherapy
Molecular Cancer, 2023 Background Cancer is the most prevalent cause of death globally, and radiotherapy is considered the standard of care for most solid tumors, including lung, breast, esophageal, and colorectal cancers and glioblastoma.
Yuehua Wu +3 more
semanticscholar +1 more source
Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Signal Transduction and Targeted Therapy, 2022 Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic effect on remote and non-irradiated tumor deposits, which is called abscopal effect.
Zengfu Zhang +3 more
semanticscholar +1 more source
JAMA Oncology, 2022 Importance To our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use of proton FLASH.
A. Mascia +17 more
semanticscholar +1 more source
Ferroptosis, radiotherapy, and combination therapeutic strategies
Protein & Cell, 2021 Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently been revealed to play an important role in radiotherapy-induced cell ...
Guang Lei +4 more
semanticscholar +1 more source
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
New England Journal of Medicine, 2005 BACKGROUND Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial
R. Stupp +18 more
semanticscholar +1 more source
Tumor Hypoxia and Radiotherapy: A Major Driver of Resistance Even for Novel Radiotherapy Modalities.
Seminars in Cancer Biology, 2023 Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy. Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic tumor cells to ionizing radiation and hypoxia-related treatment ...
Claire Beckers, M. Pruschy, I. Vetrugno
semanticscholar +1 more source
Postgraduate Medical Journal, 1974 Summary The author examines the place of radiotherapy in the management of oesophageal cancer. Many of these tumours are locally curable with radiotherapy. This is so particularly with the proliferative, poorly differentiated tumour.
openaire +2 more sources
Radiation Oncology, 2019 Purpose The purpose of this study was to assess the feasibility, efficacy and toxicity of fiducial marker implantation and tracking in CyberKnife® stereotactic radiation therapy (SBRT) applied to extracranial locations.
Nathaniel Scher +14 more
doaj +1 more source