Results 121 to 130 of about 51,676 (303)

Probabilistic optimization of dose coverage in radiotherapy

, 2019
Background and purpose: Probabilistic optimization is an alternative to margins for handling geometrical uncertainties in treatment planning of radiotherapy where uncertainties are explicitly incorporated in the optimization.
Grusell, Erik, Grusell, Erik,, Tilly, David, Holm, Asa,, Ahnesjö, Anders,, Erik Grusell, Ahnesjö, Anders, Åsa Holm, David Tilly, Holm, Asa, Tilly, David,, Anders Ahnesjö   +11 more
core   +1 more source

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Comparing Radiotherapy alone with Chemotherapy Radiotherapy in Treatment of Patients with Stage II and III Endometrial Cancer

, 2010
"nAbstract "nIntroduction: Endometrial cancer is the most common pelvic malignancy in women. Approximately 7,000 women die from this disease every year.
Mahdi Tabarrai, Hamid Attarian, Ahmad Mosavizadeh, Hamid Rezvani, Naghmeh Fatemi   +4 more
core  

Factors related to nutrition status in head and neck cancer patients receiving radiotherapy [PDF]

วิทยานิพนธ์ (พย.ม.)--จุฬาลงกรณ์มหาวิทยาลัย, 2555การศึกษาครั้งนี้มีเป็นการวิจัยเชิงบรรยาย (Descriptive research) ประเภทศึกษาหาความ สัมพันธ์ระหว่างตัวแปร (Correlation study) มีวัตถุประสงค์เพื่อศึกษาภาวะโภชนาการและปัจจัยที่มีความสัมพันธ์กับภาวะโภชนาการของผู้
บุปผา นันมา
core   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Genistein Implications in Radiotherapy: Kill Two Birds with One Stone

More than 70% of cancer patients receive radiotherapy during their treatment, with consequent various side effects on normal cells due to high ionizing radiation doses despite tumor shrinkage.
Yan Liu, Hui Wang, Ting Zhao, Yanyu Bao, Ping Li, Chao Sun, Tong Zheng, Xiongxiong Liu   +7 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source