Results 41 to 50 of about 51,676 (303)

Assessment of Different Training Methods in an Artificial Neural Network to Calculate 2D Dose Distribution in Radiotherapy [PDF]

open access: yesIranian Journal of Medical Physics, 2020
Introduction: Treatment planning is the most important part of treatment. One of the important entries into treatment planning systems is the beam dose distribution data which maybe typically measured or calculated in a long time.
Mahdi Saeedi-Moghadam   +3 more
doaj   +1 more source

Quantification of geometric uncertainties in image guided radiotherapy [PDF]

open access: yes, 2010
The aim of this thesis is to determine if the geometric uncertainties that are introduced into the image guided radiotherapy (IGRT) process by Cone Beam CT (CBCT) based IGRT equipment are sufficiently small that they do not pose a significant risk of ...
Sykes, Jonathan
core  

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Assessment of Dose Distribution and Organ-at-Risk Exposure in VMAT Versus 3D-CRT for Right Breast Cancer [PDF]

open access: yesIranian Journal of Medical Physics
Introduction: Breast cancer is one of the most common malignant tumors worldwide, and radiotherapy plays a crucial role in its treatment. This study compares Volumetric Modulated Arc Therapy (VMAT) and Three-Dimensional Conformal Radiotherapy (3D-CRT ...
Mohamed Khairat Allah   +5 more
doaj   +1 more source

Treatment Outcome of Cervical Cancer Patients at Ocean Road Cancer Institute, Dar es salaam [PDF]

open access: yes, 2011
Cervical cancer is the second commonest malignancy in females globally. Cancer of the cervix has a devastating impact on women’s health in developing countries especially Africa since more than 75% of the worldwide burden of the disease occurs in these ...
Majinge, Peter MC
core  

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Targeted radiotherapy; microgray doses and the bystander effect [PDF]

open access: yes, 2007
ndirect effects may contribute to the efficacy of radiotherapy by sterilizing malignant cells that are not directly irradiated. However, little is known of the influence of indirect effects in targeted radionuclide treatment.
Zalutsky, MR   +7 more
core   +2 more sources

The role of copper in disulfiram-induced toxicity and radiosensitisation of cancer cells.

open access: yes, 2013
Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anti-cancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome activity ...
Babich, John W   +5 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

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